Protein Alignment cysu and MPO

DIOPT Version :10

• Sequence 1: NP_650627.1
• Gene: cysu / 42100
• FlyBaseID: FBgn0038511
• Length: 753
• Species: Drosophila melanogaster
• Sequence 2: NP_000241.1
• Gene: MPO / 4353
• HGNCID: 7218
• Length: 745
• Species: Homo sapiens
• Alignment Length: 713
• Identity: 232/713 - (32%)
• Similarity: 343/713 - (48%)
• Gaps: 132/713 - (18%)

  Fly    69 TYDAINAA-YLDARKRIHVA------QPKSDWK----PEELATVGELLLDISIQLARTYGLSYEE 122
            |..|:.|| ||      |||      :.:|.|:    ..::.|..:|.:     |:::.|.:|::
Human   109 TRTAVRAADYL------HVALDLLERKLRSLWRRPFNVTDVLTPAQLNV-----LSKSSGCAYQD 162

  Fly   123 IEKGLPTIDTSKTLIREVCPPFFAGVEC-RPGKYRRFDGLCNNIEHPTWGAANAPFQRLIGPLYS 186
            :                       ||.| ...|||...|:|||...||.||:|..|.|.:...|.
Human   163 V-----------------------GVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYE 204

  Fly   187 DGIN-----APRISVTGRDLPFSRVVSRTM--HPDDGF-HDHAGTVMVIAWGQFMDHDFTLTGTP 243
            ||.:     .|.:...|..:..:|.||..:  .|.|.. .|...::|.:.|||.:|||...|..|
Human   205 DGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEP 269

  Fly   244 ------LDPINRNDPEECCKRPLHLKHPYCNEIRIPDDDYFYRLFN-VKCIDFVRGFPSPRPGCK 301
                  :..:|   .|..|     ::.|.|..::||.:|  .|:.| ..||.|.|..|: .||..
Human   270 AARASFVTGVN---CETSC-----VQQPPCFPLKIPPND--PRIKNQADCIPFFRSCPA-CPGSN 323

  Fly   302 LGSRQQFNTLTGVIDANTVYGVKESFARKLR--TGYGGLMRMNPVFQEYGLKDLLPLKLDIPDEG 364
            :..|.|.|.||..:||:.|||.:|..||.||  :...||:.:|..||:.| :.|||.. ::.|:.
Human   324 ITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNG-RALLPFD-NLHDDP 386

  Fly   365 CTRPNKS--MYCFEGGEIRVNEQLVLTCMHTLMAREHNRLATALAQINKHWDDETLFQEARRINI 427
            |...|:|  :.||..|:.|.:|...||.||||:.||||||||.|..:|..||.|.|:||||:|..
Human   387 CLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVG 451

  Fly   428 AIVQHVTFNEFLPILLGKEVMEKFGLVLQKDGYWDGYDSTVNPGIIDSFAGAAFRFGHSLLPTAV 492
            |:||.:|:.::||::||...|.|:...      :..|:.:|:|.|.:.|.. |||:||:|:...:
Human   452 AMVQIITYRDYLPLVLGPTAMRKYLPT------YRSYNDSVDPRIANVFTN-AFRYGHTLIQPFM 509

  Fly   493 ERWSKAHKFIASKRLSDLIRRPYDLYRA---GVLDEYFMGLM---------NQVAQAMDDSITQE 545
            .|....::.:.......|.|..:..:|.   |.:|....|||         ||:|       ..|
Human   510 FRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIA-------VDE 567

  Fly   546 VTNHLFKKEGARFGMDLVSFNMQRGREFGIPGYMEFRKFCGLPTSNTWDEMYGSMPNETVLR--- 607
            :...|| ::..|.|:||.:.||||.|:.|:|||..:|:|||||...|..::      .||||
Human   568 IRERLF-EQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQL------GTVLRNLK 625

  Fly   608 --------YGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRGDRFWYELPNQP 664
                    ||:    |.:||:|.|||||.......:||..||:|.||...||.|||||:|   ..
Human   626 LARKLMEQYGT----PNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWE---NE 683

  Fly   665 SSFTPEQLQEIRKAKLSRLICDNTDLIDTVQIYPMVLPDHEINPRVPCKSGIIPSIDLTKWAD 727
            ..|:.:|.|.:.:..|.|:|||||. |.||....:.:.:......|.|.:  :|:::|..|.:
Human   684 GVFSMQQRQALAQISLPRIICDNTG-ITTVSKNNIFMSNSYPRDFVNCST--LPALNLASWRE 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..699	CDD:460804	207/585 (35%)
MPO	NP_000241.1	myeloperoxidase_like	316..728	CDD:188656	160/443 (36%)