DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cysu and CG10211

DIOPT Version :9

Sequence 1:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_001286043.1	Gene:	CG10211 / 35106	FlyBaseID:	FBgn0032685	Length:	1394	Species:	Drosophila melanogaster

Alignment Length:	720	Identity:	253/720 - (35%)
Similarity:	366/720 - (50%)	Gaps:	83/720 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 YDYNVNLFRGTLNPYNNGPGTCITYDAINAAYLD---------------ARKRIHVAQPKSD-WK 94
            ::|.|...:|.::. .:..||..::...|.|.|:               .:...|:.:.|.. :.
  Fly   609 FEYEVWRTKGGISA-RSPDGTAASFSKANLAALNLANSSLIFELTSNEIVKTLNHITRRKRQIFN 672

  Fly    95 PEELATVGELLLDISIQLARTYGLSYEEIEKGLPTIDTS-------KTLIREVCPPFFAGVECRP 152
            |.:.|                  .:..|:...|.|:|.|       |.|  :.||.  ...:|..
  Fly   673 PNQNA------------------FNRNELTDTLQTVDISGLLGGAQKQL--DTCPE--PSQQCDA 715

  Fly   153 GK-YRRFDGLCNNIEHPTWGAANAPFQRLIGPLYSDGINAPRIS-VTGRDLPFSRVVSRTMHPD- 214
            .. :|...|.|||:.:|.||.:...|.||:...|.|||:|||:: |||..||..|.:|.|:|||
  Fly   716 NSPFRTLSGRCNNLRNPNWGKSLTTFSRLLPAQYEDGISAPRLTGVTGTALPNPRTISTTIHPDI 780

  Fly   215 DGFHDHAGTVMVIAWGQFMDHDFTLTGTPLDPINRNDPEE--CCKRPLHLK---HPYCNEIRIPD 274
            ...|... ::||:.:.||:|||.|||     ||::...|.  .| ||.:.:   ||.||...:|.
  Fly   781 SNLHTRY-SLMVMQFAQFVDHDLTLT-----PIHKGFHESIPSC-RPCNSRQTVHPECNPFPVPA 838

  Fly   275 DDYFYRLFNVK-----CIDFVRGFPSPRPGCKLGSRQQFNTLTGVIDANTVYGVKESFARKLRTG 334
            .|::|...||.     |...:|..|..:   .||.|.|.|..|..:|.:.|||.....:.||| |
  Fly   839 GDFYYPEVNVTSGERFCFPSMRSLPGQQ---SLGPRDQINQNTHFLDGSMVYGETTCLSNKLR-G 899

  Fly   335 YGGLMRMNPVFQEYGLKDLLPLKLDIPDEGCTRPNKSMYCFEGGEIRVNEQLVLTCMHTLMAREH 399
            :.|  |||.. |..| |:||||.   |...|  .:::..||.||:.|.:||..||.:||...|||
  Fly   900 FSG--RMNST-QVRG-KELLPLG---PHPEC--KSRNGLCFLGGDDRASEQPGLTAIHTAFLREH 955

  Fly   400 NRLATALAQINKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQKDGYWDGY 464
            ||:...|..:|.||:.|.||..||:|..|.|||:.||||||.:|....:..:||.|...||:..|
  Fly   956 NRIVEGLRGVNPHWNGEQLFHHARKIVSAQVQHIVFNEFLPRILSWNAVNLYGLKLLPQGYYKDY 1020

  Fly   465 DSTVNPGIIDSFAGAAFRFGHSLLPTAVERWSKAHKFIASK-RLSDLIRRPYDLYRAGVLDEYFM 528
            :.:.:|.:.:.||.||||.|||||...:.|.|..|:.:... .|.|...|...|.:.|::||...
  Fly  1021 NPSCSPIVFNEFAAAAFRIGHSLLRPHIPRLSVQHQPVEPPLLLRDGFFRMDALLQPGIIDEILR 1085

  Fly   529 GLMNQVAQAMDDSITQEVTNHLFKKEGARF-GMDLVSFNMQRGREFGIPGYMEFRKFCGLPTSNT 592
            ||:....:.:|..||.|||||||:.....| |:||::.|:||.|:.|||.|..:|..|.|..:..
  Fly  1086 GLVATPMETLDQFITGEVTNHLFEDRKIPFSGIDLIALNIQRARDHGIPSYNNYRALCNLKRATN 1150

  Fly   593 WDEMYGSMPNETVLRYGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRGDRFW 657
            |:::...:|.|.:.|:..|:....||||:.|.::|:.|.|.::|||.||:|..|...||:.||||
  Fly  1151 WNDLSREIPTEVINRFQKIYASVDDIDLFPGAMTERPLQGGLVGPTLACIIGIQFRQLRKCDRFW 1215

  Fly   658 YELPNQPSSFTPEQLQEIRKAKLSRLICDNTDLIDTVQIYPMVLPDHEINPRVPCKSGIIPSIDL 722
            ||..|....||..||.|:||..|::::|:|.::...:|.....||.:.:||||||.|  :|.|||
  Fly  1216 YENQNPEVKFTEAQLAEVRKVTLAKIVCENLEITGDMQRAAFDLPSNFLNPRVPCAS--MPQIDL 1278

  Fly   723 TKWAD 727
            ..|.:
  Fly  1279 NAWRE 1283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	216/550 (39%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655	155/383 (40%)
CG10211	NP_001286043.1	An_peroxidase	69..524	CDD:281139
		An_peroxidase_like	209..524	CDD:265428
		An_peroxidase	719..1245	CDD:281139	215/545 (39%)
		peroxinectin_like	871..1245	CDD:188655	155/383 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920