DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cysu and Epx

DIOPT Version :9

Sequence 1:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_001100507.1	Gene:	Epx / 303414	RGDID:	1311882	Length:	715	Species:	Rattus norvegicus

Alignment Length:	617	Identity:	212/617 - (34%)
Similarity:	311/617 - (50%)	Gaps:	81/617 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 VECRPGKYRRFDGLCNNIEHPTWGAANAPFQRLIGPLYSDGINAPRISVTGRD-----LPFSRVV 207
            ||....|||...|.|||...|..||:|....|.:...|.|..:.|.....|:.     ||..|.|
  Rat   138 VEKCSNKYRTITGRCNNRRRPWLGASNQALARWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRAV 202

  Fly   208 SRTM--HPDDGF-HDHAGTVMVIAWGQFMDHDFTLTGTPLDP--INRNDPEECCKRPLHLKHPYC 267
            |..:  .|.... .|...::|.:.||||:|||  |..||..|  :..|...:|.|....|  |.|
  Rat   203 SNQIVRFPSKKLTSDQGRSLMFMQWGQFIDHD--LDFTPESPARVTFNMGVDCEKTCAQL--PPC 263

  Fly   268 NEIRIPDDDYFYRLFNVK-CIDFVRGFPS-PRPGCKLGSRQQFNTLTGVIDANTVYGVKESFARK 330
            ..|:||.:|  .|:.:.: ||.|.|..|: |:...|:  |.|.|:||..:||:.|||.:.|.|.:
  Rat   264 FPIKIPPND--PRIKSQRDCIPFFRSAPACPQNRNKV--RNQINSLTSFVDASMVYGSEVSLALR 324

  Fly   331 L--RTGYGGLMRMNPVFQEYGLKDLLPLKLDIPDEGCTRPNK--SMYCFEGGEIRVNEQLVLTCM 391
            |  ||.|.||:..|..||:.| :.|||.. ::.::.|...|:  .:.||..|:.|.:|...|..:
  Rat   325 LRNRTNYLGLLATNQQFQDNG-RALLPFD-NLHEDPCLLTNRLVRIPCFLAGDSRASETPKLAAL 387

  Fly   392 HTLMAREHNRLATALAQINKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQ 456
            |||..||||||||.|.::|.||..:.|:.|||:|..|:||.:|:.:|||::|||..|.:
  Rat   388 HTLFVREHNRLATELKRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGKARMRR------ 446

  Fly   457 KDGYWDGYDSTVNPGIIDSFAGAAFRFGHSLLPTAVERWSKAHK-------------FIASKRLS 508
            ..|.:.||.|.|:|.:.:.|. .||||||::|...:.|....::             |.||.|:
  Rat   447 TLGPYRGYCSNVDPRVANVFT-LAFRFGHTMLQPFMFRLDSQYRTSAPNSHVLLSSAFFASWRI- 509

  Fly   509 DLIRRPYDLYRAGVLDEYFMGLMNQVAQ--AMDDSITQEVTNHLFKKEGARFGMDLVSFNMQRGR 571
                    :|..|: |....|||...|:  ..|..:..|:.:.|| ::..|.|:||.:.||||.|
  Rat   510 --------VYEGGI-DPILRGLMATPAKLNRQDSMLVDELRDKLF-QQVRRIGLDLAALNMQRSR 564

  Fly   572 EFGIPGYMEFRKFCGLPTSNTWDEMYGSMPNETVLR-YGSIFEHPADIDLWSGGVSEKSLPGSML 635
            :.|:|||..:|:||||.......::...:.|..:.| :.::::.|.:||:|.|.::|..|||:.:
  Rat   565 DHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNRNLARKFLNLYKTPDNIDIWVGAIAEPLLPGARV 629

  Fly   636 GPTFACVIATQMSYLRRGDRFWYELPNQPSSFTPEQLQEIRKAKLSRLICDNTDLIDTV------ 694
            ||..||:...|....|.|||||::   :...||..|.:.:|:..|||::||||. |.||
  Rat   630 GPLLACLFENQFRRARDGDRFWWQ---KWGVFTKRQRKALRRISLSRIVCDNTG-ISTVSRDIFR 690

  Fly   695 -QIYPMVLPDHEINPRVPCKSGIIPSIDLTKW 725
             .|||...        |.|..  ||.::|:.|
  Rat   691 ANIYPQGF--------VSCSR--IPKLNLSAW 712

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	197/568 (35%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655	142/401 (35%)
Epx	NP_001100507.1	An_peroxidase	145..679	CDD:281139	195/564 (35%)
Epx	NP_001100507.1	myeloperoxidase_like	287..699	CDD:188656	154/445 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2513
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.800