DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cysu and Nox3

DIOPT Version :9

Sequence 1:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	NP_001004216.1	Gene:	Nox3 / 292279	RGDID:	1303190	Length:	568	Species:	Rattus norvegicus

Alignment Length:	380	Identity:	66/380 - (17%)
Similarity:	103/380 - (27%)	Gaps:	183/380 - (48%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSLAAVAHAQYHQFG-EQLQTAHGSDCALLLAGPGRSSVYDYNVNLFRGTLNPYNNGPGTCITYD 71
            :::.:|.|...|.|. |:.......|...|||                 .|:...|.|
  Rat   109 IAVNSVIHIVAHLFNLERYHLGQAKDAEGLLA-----------------ALSKLGNAP------- 149

  Fly    72 AINAAYLDARKRIHVAQPKSDWKPEELATVGELLLDISIQLARTYGLSYEEIEKGLPTIDTSKT- 135
              |.:||:..:.::.            .|..:||:.:|       |::...|...|..|.||.|
  Rat   150 --NESYLNPVRTLYT------------GTTTQLLMTVS-------GITGLVISLALILIMTSSTE 193

  Fly   136 LIRE--------------------------------------------------------VCP-P 143
            .||:                                                        .|| |
  Rat   194 FIRQSSYELFWYTHHIFIFLFISLAIHGGGRIIRGQTPESLRLHNVTFCRDHFDEWQEAASCPVP 258

  Fly   144 FFAGVECRPGKYRRFDGLCNNIEHPTWGAANAPFQRLIGP--LYSDGINAPRISVTGRDLPFSRV 206
            .|:|.|  |..::             |         .:||  ||:..| ..|...:.:::..::|
  Rat   259 QFSGKE--PSAWK-------------W---------TLGPVVLYACEI-IIRFWRSHQEVVITKV 298

  Fly   207 VSRTMHPDDGFHDH-----------------AGTVMVIAWGQFMDHDFTLTGTPLDPI------- 247
            ||   ||......|                 ..::..:.|     |.||||..|.:..
  Rat   299 VS---HPSAVLELHMKKRDFKMAPGQYIFIQCPSISPLEW-----HPFTLTSAPQEDFFSVHIRA 355

  Fly   248 --------------NRNDPEECCKRP-LHLKHPYCNEIRIPDDDYFYRLFNVKCI 287
                          ....|.|.|..| |.:..|:...:.    |.|:...:| ||
  Rat   356 SGDWTEALLKAFGAEGQAPSELCSMPRLAVDGPFGGSLA----DVFHYPVSV-CI 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	31/174 (18%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655
Nox3	NP_001004216.1	Ferric_reduct	66..217	CDD:280043	28/152 (18%)
Nox3	NP_001004216.1	NOX_Duox_like_FAD_NADP	295..568	CDD:99783	24/124 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910