DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cysu and Lpo

DIOPT Version :9

Sequence 1:	NP_650627.1	Gene:	cysu / 42100	FlyBaseID:	FBgn0038511	Length:	753	Species:	Drosophila melanogaster
Sequence 2:	XP_006247147.1	Gene:	Lpo / 287610	RGDID:	1310051	Length:	710	Species:	Rattus norvegicus

Alignment Length:	714	Identity:	234/714 - (32%)
Similarity:	345/714 - (48%)	Gaps:	96/714 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 CITYD----AINAAYLDARKRIHVAQPKSDWKPEELATVGELLLDISIQLART-----YGLSYEE 122
            |.|.:    ::|.|:||:|.|:..|.      ..|:.:...|...:.....||     .|..:||
  Rat    35 CDTVEEVKASVNKAFLDSRSRLKKAM------SAEVRSTRHLSDYLKHAKGRTRTAIRNGQVWEE 93

  Fly   123 IEKGLPTIDTSKT--------LIREV-CPPFFAGVECR-PGKYRRFDGLCNNIEHPTWGAANAPF 177
            ..|.|....|:.|        |..:| |.|....|.|. ...||...|.|||.::|..|:||...
  Rat    94 SLKKLTQFLTNATGQGLDLTSLFWKVGCNPPAPAVTCNISNPYRTITGDCNNRKNPALGSANRAL 158

  Fly   178 QRLIGPLYSDGIN-----APRISVTGRDLPFSRVVSRT----MHPDDGFHDHAGTVMVIAWGQFM 233
            .|.:...|.||::     .|..:..|..||..|.||..    ::.:|.. |...:|:.:.|||.:
  Rat   159 ARWLPAEYEDGLSLPFGWTPGKTRNGYPLPQPREVSNQIAGYLNEEDVL-DQKRSVLFMQWGQIV 222

  Fly   234 DHDF-----TLTGTPLDPINRNDPEECCKRPLHLKHPYCNEIRIPDDDYFYRLFNVKCIDFVR-G 292
            |||.     |..||  |...:...:|.|     ::...|..|..|..|...:. ..||:.|.| |
  Rat   223 DHDLDFAPDTEMGT--DNYTKAQCDEHC-----IQGDNCFPIMFPTGDPKLKT-QGKCMSFFRAG 279

  Fly   293 FPSPRPGCKLGSRQQFNTLTGVIDANTVYGVKESFARKLR--TGYGGLMRMNPVFQEYGLKDLLP 355
            |..|.|..:..:|:|.|.||..:||:.||..:.|.|.:||  :...|||.:|....::|..  .|
  Rat   280 FVCPTPPYQSLTREQINALTSFLDASLVYSPEPSMANRLRNLSSPLGLMAVNEEVSDHGRP--FP 342

  Fly   356 LKLDIPDEGCTRPNKS--MYCFEGGEIRVNEQLVLTCMHTLMAREHNRLATALAQINKHWDDETL 418
            ..:.:....|...|.:  :.||..|:.|.:||::|...|||..|||||||..|:.:|.|||.|||
  Rat   343 PFVKMKPSPCEVINATAGVPCFLAGDSRASEQILLATSHTLFIREHNRLARELSTLNPHWDGETL 407

  Fly   419 FQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQKDGYW----DGYDSTVNPGIIDSFAGA 479
            :||.|:|..|.:|.:||.::||||||.|        :||   |    .||:.:|:|.|.:.|. .
  Rat   408 YQETRKIMGAFIQIITFRDYLPILLGDE--------MQK---WIPPYQGYNESVDPRISNVFT-F 460

  Fly   480 AFRFGHSLLPTAVERWSKAHKFIASK---RLSDLIRRPYDLYRAGVLDEYFMGLMNQVAQAM--D 539
            ||||||..:|:.|.|..:.::...|:   .|..:....:.|.:.|.:|....||:.:.|:.|  |
  Rat   461 AFRFGHLEIPSTVSRLDENYQPWGSEPELPLHTVFFNTWRLVKDGGIDPLVRGLLAKKAKLMHQD 525

  Fly   540 DSITQEVTNHLFKKEGARFGMDLVSFNMQRGREFGIPGYMEFRKFCGLPTSNTWDEMYGSMPNET 604
            ..:|.|:.|.||:......|.||.|.|:||.|:.|:|||..:|.||||....|.:|:...|.||.
  Rat   526 RMMTGELRNKLFQPTHTIHGFDLASINIQRCRDHGMPGYNSWRAFCGLSQPKTLEELSAVMENEV 590

  Fly   605 VLR-----YGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRGDRFWYELPNQP 664
            :.:     ||:    |::||:|.|.::|..:||..:||...|::..|...:|.|||||:|   .|
  Rat   591 LAKKLLDLYGT----PSNIDIWLGAIAEPLVPGGRVGPLLTCLLGHQFQRVRDGDRFWWE---NP 648

  Fly   665 SSFTPEQLQEIRKAKLSRLICDNTDLIDTVQIYPMVLPDHEINPR--VPCKSGIIPSIDLTKWA 726
            ..||.:|.:.::|...|||:||||. |..|.:.|.:...:   |.  |.|.|  :..:||:.||
  Rat   649 GVFTEKQRESLQKLSFSRLVCDNTG-ITKVPLNPFLANTY---PHGFVDCSS--VDKLDLSPWA 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..692	CDD:281139	197/569 (35%)
cysu	NP_650627.1	peroxinectin_like	305..687	CDD:188655	146/399 (37%)
Lpo	XP_006247147.1	An_peroxidase	136..675	CDD:281139	197/569 (35%)
Lpo	XP_006247147.1	myeloperoxidase_like	281..692	CDD:188656	155/435 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343960
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2513
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.800