Protein Alignment cysu and tpo

DIOPT Version :10

• Sequence 1: NP_650627.1
• Gene: cysu / 42100
• FlyBaseID: FBgn0038511
• Length: 753
• Species: Drosophila melanogaster
• Sequence 2: XP_031758614.1
• Gene: tpo / 100036738
• XenbaseID: XB-GENE-920152
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 235/652 - (36%)
• Similarity: 336/652 - (51%)
• Gaps: 82/652 - (12%)

  Fly   117 GLSYEEIEKGLPTIDTSKTLIREVCPPFFAGVECRPGKYRRFDGLCNNIEHPTWGAANAPFQRLI 181
            |.|:|.:...| |....:|| ...||.     .|..||||...|.|||..:|.|||||....|.:
 Frog    69 GSSFEAVLANL-TGCVPQTL-SPFCPN-----NCLAGKYRHITGACNNRNNPAWGAANTLLARWL 126

  Fly   182 GPLYSDGINAPR-----ISVTGRDLPFSR-VVSRTMHP------DDGFHDHAGTVMVIAWGQFMD 234
            ...|.|||..|:     ....|..||..| |.::.:|.      :|..:.|    ::|.|||::|
 Frog   127 PAQYEDGIGEPKGWREEFLYNGFRLPQVREVTNKIIHASSKAFREDDLYSH----IIIEWGQYID 187

  Fly   235 HDFTLT-----GTPLDPINRNDPEECCKRPLHLKHPYCNEIRIPDDDYFYRLFNVKCIDFVRGFP 294
            ||...|     .||  .|...|    ||......:| |..|::.::|   .|....||.|.|...
 Frog   188 HDIAFTPQSVSKTP--AIGSVD----CKSTCENLYP-CYPIKLSEED---PLSQGGCIPFYRSSS 242

  Fly   295 ---SPRPGCKLGS------RQQFNTLTGVIDANTVYGVKESFARKLR--TGYGGLMRMNPVFQEY 348
               :.|.|.|.|:      |:|.|.||..|||:||||..||...||:  :...||:|:|..:.:
 Frog   243 ACGTGRGGLKFGNPSLLNPREQINGLTSFIDASTVYGSSESLQHKLKNLSSEEGLLRVNVKYSD- 306

  Fly   349 GLKDLLPLKLDIPDEGCTRPN----KSMYCFEGGEIRVNEQLVLTCMHTLMAREHNRLATALAQI 409
            ..::.||  .:.|......|.    :.:.||..||.|.||.:.|..:|||..|||||:|.||.::
 Frog   307 SSREYLP--FETPSACMQDPTADNAERIDCFFAGEGRANEVITLAAVHTLWLREHNRIAKALKKL 369

  Fly   410 NKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQKDGYWDGYDSTVNPGIID 474
            |.||:.||.:||||:|..|:.|.:||.:::|.:|||...:::      .|.:.||:...||.|.:
 Frog   370 NPHWNSETTYQEARKIVGALHQIITFRDYMPKILGKAAYDQY------IGLYKGYNQKTNPSISN 428

  Fly   475 SFAGAAFRFGHSLLPTAVERWSKAH----KFIASKRLSDLIRRPYDLYRAGVLDEYFMGLMNQVA 535
            .|..|||||||:.:|..|.|.:..:    |: .|..|:::..||:.:.:.|.||....||:.:.|
 Frog   429 IFTTAAFRFGHATIPPMVHRLNSQYVDDPKY-PSLPLNEVFFRPWRIVKEGGLDPLIRGLLGKSA 492

  Fly   536 --QAMDDSITQEVTNHL--FKKEGARFGMDLVSFNMQRGREFGIPGYMEFRKFCGLPTSNTWDEM 596
              |...|.|.:|:|..|  ....|:   |||.|.|:||||:.|:|||.::|:||||....|..::
 Frog   493 KLQTQVDMINEELTEKLLVMTNNGS---MDLASLNLQRGRDHGLPGYNDWREFCGLSRLATPADL 554

  Fly   597 YGSMPNE-TVLRYGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRGDRFWYEL 660
            ..::.:: .|.:..:::.||.:||:|.||::|..|||:..||.|||:|..||..||.|||||||.
 Frog   555 INAVSDQKLVAKMIALYSHPDNIDVWLGGLAEDFLPGARTGPLFACLIGKQMQALREGDRFWYEN 619

  Fly   661 PNQPSSFTPEQLQEIRKAKLSRLICDNTDLIDTVQIYPMVLPDHEINPRVPCKSGIIPSIDLTKW 725
            .|   .||..|..|:.|..|||:|||||.| ..|.:...:|.::..| .|.|.|  ||.|:|..|
 Frog   620 NN---IFTKIQRSELEKHSLSRVICDNTGL-SHVPLDAFLLGNYPDN-FVSCDS--IPGINLEAW 677

  Fly   726 AD 727
            .:
 Frog   678 KE 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cysu	NP_650627.1	An_peroxidase	155..699	CDD:460804	213/584 (36%)
tpo	XP_031758614.1	thyroid_peroxidase	116..679	CDD:188657	215/596 (36%)
		CCP	687..736	CDD:153056
		EGF_CA	738..781	CDD:214542