Protein Alignment CG5863 and NAPSA

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_004842.1
• Gene: NAPSA / 9476
• HGNCID: 13395
• Length: 420
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 153/393 - (38%)
• Similarity: 214/393 - (54%)
• Gaps: 40/393 - (10%)

  Fly    25 LIRIPMQFQASFMASRRQHRA--GRSSLLAKYNVVGG--QEVTSRNGGATE--------TLDNRL 77
            |||||:            ||.  ||..|    |::.|  :.......||..        .|.|..
Human    26 LIRIPL------------HRVQPGRRIL----NLLRGWREPAELPKLGAPSPGDKPIFVPLSNYR 74

  Fly    78 NLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPDGRRFSI 142
            :::|.|.|.:|:|.|.|.:.|||||:||||||..|...||.|..|||::..|||:|..:|.:|:|
Human    75 DVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAI 139

  Fly   143 AYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELGIKPLFE 207
            .||||.:.|.|::|.:.||.:...:..||.|..||...|...:|.||:||||..::..|::|..:
Human   140 QYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMD 204

  Fly   208 SMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLDVIEVAG 272
            .:.:|.|:|:.||||||.|:..|..||||:.||.|...:...||:||:|...|||..::.::|..
Human   205 VLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGP 269

  Fly   273 --TRINQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSEIDSLPEIVFIIGGQR 335
              |...:...||.||||||:..|..|...:::.:||:|....||::.||||..||.:.|::||..
Human   270 GLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVW 334

  Fly   336 FGLQPRDYVMSATNDDGSSICLSAFTLMD-----AEFWILGDVFIGRYYTAFDAG----QRRIGF 391
            |.|...|||:..|. :|..:|||.|..:|     ..||||||||:|.|...||.|    ..|:|.
Human   335 FNLTAHDYVIQTTR-NGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGL 398

  Fly   392 APA 394
            |.|
Human   399 ARA 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	137/339 (40%)
		Asp	80..394	CDD:278455	136/324 (42%)
NAPSA	NP_004842.1	pepsin_retropepsin_like	72..399	CDD:299705	136/327 (42%)
		Asp	77..401	CDD:278455	136/324 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.790