Protein Alignment CG5863 and bace1

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001072485.1
• Gene: bace1 / 779940
• XenbaseID: XB-GENE-5787150
• Length: 502
• Species: Xenopus tropicalis
• Alignment Length: 415
• Identity: 103/415 - (24%)
• Similarity: 173/415 - (41%)
• Gaps: 67/415 - (16%)

  Fly    23 GQL-IRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATETLDNRLNLEYAGPIS 86
            ||: |::|:: ......|...:||.||:       ..|.|:.:......:.|..:....|...:.
 Frog    25 GQVAIKLPLK-NCPGTCSPMAYRAKRSA-------EKGMELDTNFLDMIDNLRGKSGQGYYVEMR 81

  Fly    87 IGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPDGRRFSIAYGTGSLSG 151
            :|:|.|..|:|.||||:|..|.:|   |......::||.:   |.|:....|...:.|..|...|
 Frog    82 VGTPPQTLNILVDTGSSNFAVGAA---PHPFLKRYYHRQH---SRTYRDVRRGVYVPYTQGKWEG 140

  Fly   152 RLAQDTVAI--GQLVVQNQTFGMATHEPGPTFVD-TNFAGIVGLGFRPIA--ELGIKPLFESMCD 211
            .|..|.|.|  |..|.........| :....|:: :|:.||:||.:..||  :..::|.|:|:..
 Frog   141 ELGTDLVTIPHGPNVTVTANIAAIT-DSDKFFINGSNWEGILGLAYAEIARPDDTLEPFFDSLVK 204

  Fly   212 QQLVDECVFSFYLKRNG--------SERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLDVI 268
            |..|.. :||..|...|        |...||.::.||:|.:.:.||:.|.|:....|::..:..|
 Frog   205 QTRVPN-IFSLQLCGTGFHFNESDTSASVGGSMVIGGIDPSLYIGSIWYTPIRKEWYYEVIIVKI 268

  Fly   269 EVAGTRINQN------RQAIADTGTSLLAAPPREY-LIINSLLGGLPTSN-------NEYLLNCS 319
            |:.|..::.:      .::|.|:||:.|..|.|.: ..:.|:.....|..       .|.|: |.
 Frog   269 EINGQDLHMDCKEYNYDKSIVDSGTTNLRLPKRVFDAAVKSIKAASSTEKFPDGFWLGEQLV-CW 332

  Fly   320 EIDSLPEIVF---------IIGGQRFG--------LQPRDYVMSATNDDGSSICLSAFTLMDAEF 367
            :..:.|..:|         .:..|.|.        |:|.:.:.:|..|     |...........
 Frog   333 QEGTTPWHIFPVISLYLMGEVANQSFKITILPQQYLRPVEDIATAQED-----CYKFAVSQSTTG 392

  Fly   368 WILGDVFIGRYYTAFDAGQRRIGFA 392
            .::|.|.:..:|..||...:|||||
 Frog   393 TVMGAVIMEGFYVVFDRANKRIGFA 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	90/364 (25%)
		Asp	80..394	CDD:278455	91/357 (25%)
bace1	NP_001072485.1	beta_secretase_like	73..438	CDD:133140	91/359 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910