DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5863 and mgc108380

DIOPT Version :9

Sequence 1:	NP_650623.1	Gene:	CG5863 / 42096	FlyBaseID:	FBgn0038507	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001027480.1	Gene:	mgc108380 / 613072	-ID:	-	Length:	384	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	137/412 - (33%)
Similarity:	215/412 - (52%)	Gaps:	54/412 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WLSLWILCLFWAKCQGQLIRIPMQFQAS-------------FMASRRQHRAGRSSLLAKYNVVGG 59
            |:.|..:||   :....|:|:|::...|             ||.:.::..|.:.....||:....
Frog     3 WVVLAFICL---QLSEGLVRVPLKRYKSARDIMRERGILKEFMKTHKRDPALKYHFNEKYDFAVA 64

  Fly    60 QEVTSRNGGATETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHR 124
            .|            ...::..|.|.||||:|.|.|.:||||||:||||||..|  :|.||.:|:.
Frog    65 YE------------PMYMDTYYYGEISIGTPPQNFLVLFDTGSSNLWVPSTSC--QSEACSNHNL 115

  Fly   125 YNASASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGI 189
            :|.|.|||:..:|::||::||:||::|....|||.:..|.:.||.||:...|.|.:|..:.|.||
Frog   116 FNPSQSSTYTSNGQQFSMSYGSGSVTGVFGYDTVTVQGLSLNNQEFGLTYTESGSSFYYSKFDGI 180

  Fly   190 VGLGFRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVP 254
            .|:.:..::..|.....:.|..|.|:...:||.|:     ..:.||::|||||...:||.:.:.|
Frog   181 FGMAYPAMSAGGATTAMQGMLQQNLLTYPIFSVYM-----SSQSGEVIFGGVDNNLYSGQIQWSP 240

  Fly   255 LTHAGYWQFPLDVIEVAGTR---INQNRQAIADTGTSLLAAPPREYL--IINSLLGGLPTSNNEY 314
            :|...|||..:|...:.|..   .:|..|||.|||||.|.. |::|:  ::.:|  |....|..:
Frog   241 VTQEVYWQIGIDEFLINGQATGWCSQGCQAIVDTGTSPLTI-PQQYMGTLLQNL--GAQNYNGMF 302

  Fly   315 LLNCSEIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAF--TLMDAE----FWILGDV 373
            ::||:.:.:||.|.|:|.|.:|.:.|..|::. ||    ..|....  |.:.::    .||||||
Frog   303 VVNCNSVQNLPTITFVINGVQFPIPPSGYIVQ-TN----GYCTVGVEETYLPSQNGQPLWILGDV 362

  Fly   374 FIGRYYTAFDAGQRRIGFAPAA 395
            |:.:||:.:|....|:|||.||
Frog   363 FLRQYYSVYDMSNNRVGFAQAA 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	119/331 (36%)
CG5863	NP_650623.1	Asp	80..394	CDD:278455	121/324 (37%)
mgc108380	NP_001027480.1	A1_Propeptide	17..45	CDD:369623	6/27 (22%)
mgc108380	NP_001027480.1	pepsin_retropepsin_like	71..383	CDD:386101	121/326 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930