Protein Alignment CG5863 and PGC

DIOPT Version :10

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_002621.1
• Gene: PGC / 5225
• HGNCID: 8890
• Length: 388
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 140/401 - (34%)
• Similarity: 220/401 - (54%)
• Gaps: 28/401 - (6%)

  Fly     8 WLSLWILCLFWAKCQGQLIRIPM-QFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATE 71
            |:.:.::||  ...:..::::|: :|::.....:.:...|......||:...    ..|.|..:.
Human     3 WMVVVLVCL--QLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAW----KYRFGDLSV 61

  Fly    72 TLDNR--LNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFV 134
            |.:..  ::..|.|.||||:|.|.|.:||||||:||||||..|  :|.||..|.|:|.|.|||:.
Human    62 TYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC--QSQACTSHSRFNPSESSTYS 124

  Fly   135 PDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAE 199
            .:|:.||:.||:|||:|....||:.:..:.|.||.||::.:|||..||...|.||:||.:..::.
Human   125 TNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSV 189

  Fly   200 LGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFP 264
            .......:.|..:..:...|||.||. |.....||.::|||||.:.::|.:.:.|:|...|||..
Human   190 DEATTAMQGMVQEGALTSPVFSVYLS-NQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIG 253

  Fly   265 LDVIEVAGTR---INQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEY---LLNCSEIDS 323
            ::...:.|..   .::..|||.|||||||.. |::|:  ::||.......:||   |:||:.|.:
Human   254 IEEFLIGGQASGWCSEGCQAIVDTGTSLLTV-PQQYM--SALLQATGAQEDEYGQFLVNCNSIQN 315

  Fly   324 LPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMDAE----FWILGDVFIGRYYTAFDA 384
            ||.:.|||.|..|.|.|..|::|  |:...::.:.. |.:.::    .|||||||:..||:.:|.
Human   316 LPSLTFIINGVEFPLPPSSYILS--NNGYCTVGVEP-TYLSSQNGQPLWILGDVFLRSYYSVYDL 377

  Fly   385 GQRRIGFAPAA 395
            |..|:|||.||
Human   378 GNNRVGFATAA 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	Asp	80..394	CDD:394983	127/323 (39%)
PGC	NP_002621.1	A1_Propeptide	20..46	CDD:462326	3/25 (12%)
		gastricsin	70..387	CDD:133144	127/325 (39%)