Protein Alignment CG5863 and Bace

DIOPT Version :10

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 178/389 - (45%)
• Similarity: 250/389 - (64%)
• Gaps: 17/389 - (4%)

  Fly     7 LWLSLWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATE 71
            ::.::.::.|..|....:|.|:|:..:.:|:.:|:...|.:|.|..||.:...:.|..      |
  Fly     1 MFKTIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDE------E 59

  Fly    72 TLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPD 136
            .|.|.:|:.|.|.||||:|.|.|.:|||:||:||||||..|  ||.||..|::|::|||||:|.:
  Fly    60 QLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTC--KSDACLTHNQYDSSASSTYVAN 122

  Fly   137 GRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELG 201
            |..|||.||||||:|.|:.|||.:..|.:|:|||..:|:|||..|.|.||.||:|:.:..:|..|
  Fly   123 GESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDG 187

  Fly   202 IKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLD 266
            :.|.|.:|..|.|||..||||||.|:|:...||||:|||.|.:.:||:|||||::..|||||.:.
  Fly   188 VAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMA 252

  Fly   267 VIEVAGTRINQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSEIDSLPEIVFII 331
            ...:.|..:..:.||||||||||:.||...|:.::.:|.   ...:.| |:||.:.|||::.|.|
  Fly   253 GSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILN---VGEDGY-LDCSSVSSLPDVTFNI 313

  Fly   332 GGQRFGLQPRDYVMSATNDDGSSICLSAFTLMDAEFWILGDVFIGRYYTAFDAGQRRIGFAPAA 395
            ||..|.|:|..|::.:   ||:  |:|||..|..:||||||||||:|||.||.|..||||||.|
  Fly   314 GGTNFVLKPSAYIIQS---DGN--CMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFAPVA 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	Asp	80..394	CDD:394983	159/313 (51%)
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	161/320 (50%)