Protein Alignment CG5863 and napsa

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_956325.1
• Gene: napsa / 336746
• ZFINID: ZDB-GENE-030131-8690
• Length: 412
• Species: Danio rerio
• Alignment Length: 417
• Identity: 160/417 - (38%)
• Similarity: 232/417 - (55%)
• Gaps: 42/417 - (10%)

  Fly     9 LSLWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGR----------SSLLAKYNVVGGQEVT 63
            |..:::.|..|..|. :||||:.    .|.:.|:..|..          :.:.|||:     :.|
Zfish     6 LFAFLIGLLIADSQA-IIRIPLH----KMRTVRRMLADNGKTIDEIKSLAKMKAKYS-----DGT 60

  Fly    64 SRNGGA--------------TETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSP 114
            ..|.|:              .|.|.|.::.:|.|.||||:|.|.|::||||||:||||||..|:.
Zfish    61 FTNQGSVTIPAPTTTQLPPPVEKLTNFMDAQYYGMISIGTPPQDFSVLFDTGSSNLWVPSIHCAF 125

  Fly   115 KSVACHHHHRYNASASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGP 179
            ..:||..|.|||:..|||:|.:|..|||.||.|||||.::||||.:..|.|..|.|..|..:||.
Zfish   126 LDIACWLHRRYNSKKSSTYVQNGTEFSIQYGRGSLSGFISQDTVNLAGLNVTGQQFAEAVKQPGI 190

  Fly   180 TFVDTNFAGIVGLGFRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKT 244
            .|....|.|::|:.:..|:...:.|:|::....:::.:.:||||:.|:.:...||||:.||.|:.
Zfish   191 VFAVARFDGVLGMAYPAISVDRVTPVFDTAMAAKILPQNIFSFYINRDPAGDVGGELMLGGFDQQ 255

  Fly   245 KFSGSLTYVPLTHAGYWQFPLDVIEVAG--TRINQNRQAIADTGTSLLAAPPREYLIINSLLGGL 307
            .|:|.|.||.:|...|||..:|.::|..  |......|||.|||||::..|.:|...:...:|.:
Zfish   256 YFNGDLHYVNVTRKAYWQIKMDEVQVGSTLTLCKSGCQAIVDTGTSMITGPVQEVRALQKAIGAI 320

  Fly   308 PTSNNEYLLNCSEIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD-----AEF 367
            |....||.::|.:|.:||.:.|.:||:.|.|..::|||..:: .|.::|||.|..||     ...
Zfish   321 PLLMGEYWIDCKKIPTLPVVSFSLGGKMFNLTGQEYVMKMSH-MGMNVCLSGFMAMDIPPPAGPL 384

  Fly   368 WILGDVFIGRYYTAFDAGQRRIGFAPA 394
            |||||||||||||.||..|.|:|||||
Zfish   385 WILGDVFIGRYYTVFDRDQDRVGFAPA 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	139/327 (43%)
		Asp	80..394	CDD:278455	138/320 (43%)
napsa	NP_956325.1	A1_Propeptide	21..48	CDD:285240	7/30 (23%)
		Cathepsin_D2	86..410	CDD:133157	138/324 (43%)
		Asp	91..411	CDD:278455	138/320 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100536
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.790