Protein Alignment CG5863 and Ren

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_036774.4
• Gene: Ren / 24715
• RGDID: 3554
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 145/405 - (35%)
• Similarity: 215/405 - (53%)
• Gaps: 28/405 - (6%)

  Fly     9 LSLWILCLFWAKCQGQLIRIPMQFQASF-------MASRRQHRAGRSSLLAKYNVVGGQEV---T 63
            :.||.|.|.|..|.   ..:|.. .|||       |.|.|:....|...:.:.:...|:.:   :
  Rat     6 MPLWALLLLWTSCS---FSLPTD-TASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSS 66

  Fly    64 SRNGGATETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNAS 128
            ..|..:...|.|.|:.:|.|.|.||:|.|.|.::||||||||||||.:|.|...||..|:.|::|
  Rat    67 FTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSS 131

  Fly   129 ASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLG 193
            .||:::.:|..|:|.||:|.:.|.|:||.|.:|.::| .||||..|..|...|:...|.|::|:|
  Rat   132 ESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIV-TQTFGEVTELPLIPFMLAKFDGVLGMG 195

  Fly   194 FRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHA 258
            |...|..|:.|:|:.:..|:::.|.|||.|..|. |...|||::.||.|...:.|:..||.::.|
  Rat   196 FPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRE-SHLLGGEVVLGGSDPQHYQGNFHYVSISKA 259

  Fly   259 GYWQFPLDVIEVAGTRI--NQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSEI 321
            |.||..:..:.|....:  .:...|:.|||||.::.|.....:|...||......|.|::|||::
  Rat   260 GSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNCSQV 324

  Fly   322 DSLPEIVFIIGGQRFGLQPRDYVMS--ATNDDGSSICLSAFTLMD-----AEFWILGDVFIGRYY 379
            .:||:|.|.:||:.:.|...|||..  ..|||   :|:.|...:|     ...|:||..||.::|
  Rat   325 PTLPDISFYLGGRTYTLSNMDYVQKNPFRNDD---LCILALQGLDIPPPTGPVWVLGATFIRKFY 386

  Fly   380 TAFDAGQRRIGFAPA 394
            |.||....|||||.|
  Rat   387 TEFDRHNNRIGFALA 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	126/329 (38%)
		Asp	80..394	CDD:278455	125/322 (39%)
Ren	NP_036774.4	A1_Propeptide	31..64	CDD:400357	5/32 (16%)
		renin_like	76..401	CDD:133154	128/329 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.890