Protein Alignment CG5863 and Ren1

DIOPT Version :10

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 404
• Identity: 144/404 - (35%)
• Similarity: 211/404 - (52%)
• Gaps: 26/404 - (6%)

  Fly     9 LSLWILCLFWAKCQGQL-------IRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSR- 65
            :.||.|.|.|:.|...|       .|||::...|......:.....:.|.|::.|     .|.|
Mouse     6 MPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGV-----FTKRP 65

  Fly    66 ---NGGATETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNA 127
               |..:...|.|.||.:|.|.|.||:|.|.|.::||||||||||||.:||...:||..|..|.:
Mouse    66 SLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130

  Fly   128 SASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGL 192
            |.||:::.:|..|:|.||:|.:.|.|:||:|.:|.:.| .||||..|..|...|:...|.|::|:
Mouse   131 SDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGM 194

  Fly   193 GFRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTH 257
            ||...|..|:.|:|:.:..|.::.|.|||.|..| ||...|||::.||.|...:.|:..||.::.
Mouse   195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNR-GSHLLGGEVVLGGSDPQHYQGNFHYVSISK 258

  Fly   258 AGYWQFPLDVIEVAGTRI--NQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSE 320
            ...||..:..:.|..:.:  .:....:.|||:|.::||.....:|...||.......||::|||:
Mouse   259 TDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQ 323

  Fly   321 IDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD-----AEFWILGDVFIGRYYT 380
            :.:||:|.|.:||:.:.|...|||:...| ....:|..|...||     ...|:||..||.::||
Mouse   324 VPTLPDISFDLGGRAYTLSSTDYVLQYPN-RRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYT 387

  Fly   381 AFDAGQRRIGFAPA 394
            .||....|||||.|
Mouse   388 EFDRHNNRIGFALA 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	Asp	80..394	CDD:394983	122/320 (38%)
Ren1	NP_112469.1	A1_Propeptide	31..>49	CDD:462326	4/17 (24%)
		renin_like	76..401	CDD:133154	126/327 (39%)