DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5863 and asp-13

DIOPT Version :9

Sequence 1:	NP_650623.1	Gene:	CG5863 / 42096	FlyBaseID:	FBgn0038507	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_505232.1	Gene:	asp-13 / 179247	WormBaseID:	WBGene00017881	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	106/369 - (28%)
Similarity:	164/369 - (44%)	Gaps:	37/369 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATETLDNRLNLEYAGPISIGSPGQPFNMLFD 99
            :::..|.:..|.|||.||.               ..::..:.:..||.|.|::|:|.|.|.::.|
Worm    41 AYLEYRDRMVASRSSNLAT---------------VVQSTTDYVYYEYMGNITVGTPDQNFIVVLD 90

  Fly   100 TGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIG--- 161
            ||||||.:|...|   :..|.....:|..||||::...|.:.|.|.:|...|.|..|||.||
Worm    91 TGSANLLIPGTNC---TTYCEKKRLFNEKASSTYIATNRPWQIKYASGDAYGTLGIDTVKIGGSG 152

  Fly   162 --QLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELGIKPLFESMCDQQLVDECVFSFYL 224
              ||.:.....|:| ...|..|..:...||.||.|..:|...|.|...:..:|.|:|:.:|:.:.
Worm   153 EAQLAIPRSYLGVA-DTVGSDFKWSPKEGIFGLAFTALAVDNITPPIINAINQGLLDQPLFTTWF 216

  Fly   225 KRNGS--ERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLDVIEVAGTRINQNRQAIADTGT 287
            .:.|:  ....|...:||:||......:.|..||:|.::||......:.........:.|.||.|
Worm   217 GQRGAPGTSASGAFTYGGLDKNHCGPVIGYAELTNARHFQFQATGFSLGSYVSTTTYEVITDTAT 281

  Fly   288 SLLAAPPREYLIINSLLGGL--PTSNNEYLLNCSEIDSLPEIVFIIGGQRFGLQPRDYVMSATND 350
            |.|..|......:....|..  || |..:.:.| :.|:.| |...||...:.::..:|::..
Worm   282 SFLCGPQAAIDNLAKAAGATWDPT-NQVFNIPC-DADAGP-IKMKIGQFNYVIRANNYILKI--- 340

  Fly   351 DGSSICLSAFTLMDAEF---WILGDVFIGRYYTAFDAGQRRIGF 391
            |.:|...:|.....|.|   ||||..|:.:|....|.||:|:||
Worm   341 DTNSCLFAAIPQNYAGFGPSWILGGPFMRQYCNVHDIGQKRVGF 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	99/333 (30%)
CG5863	NP_650623.1	Asp	80..394	CDD:278455	99/324 (31%)
asp-13	NP_505232.1	Asp	71..384	CDD:365818	97/322 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920