Protein Alignment CG5863 and Ctsd

DIOPT Version :10

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_599161.2
• Gene: Ctsd / 171293
• RGDID: 621511
• Length: 407
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 166/406 - (40%)
• Similarity: 231/406 - (56%)
• Gaps: 29/406 - (7%)

  Fly    11 LWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGRSSL--------LAKYNVVGGQEVTSRNG 67
            |.||.|. |.....|||||::   .|.:.||.......|:        :.||::   |.......
  Rat     8 LLILGLL-AASSSALIRIPLR---KFTSIRRTMTEVGGSVEDLILKGPITKYSM---QSSPRTKE 65

  Fly    68 GATETLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASST 132
            ..:|.|.|.|:.:|.|.|.||:|.|.|.::|||||:||||||..|....:||..||:||:..|||
  Rat    66 PVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSST 130

  Fly   133 FVPDGRRFSIAYGTGSLSGRLAQDTVAI------GQLVVQNQTFGMATHEPGPTFVDTNFAGIVG 191
            :|.:|..|.|.||:|||||.|:||||::      |.:.|:.|.||.||.:||..|:...|.||:|
  Rat   131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILG 195

  Fly   192 LGFRPIAELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLT 256
            :|:..|:...:.|:|:::..|:||::.:|||||.|:.:.:.||||:.||.|...:.|.|:|:.:|
  Rat   196 MGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNVT 260

  Fly   257 HAGYWQFPLDVIEVAG--TRINQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCS 319
            ...|||..:|.:||..  |......:||.|||||||..|..|...:...:|.:|....||::.|.
  Rat   261 RKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGEYMIPCE 325

  Fly   320 EIDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD-----AEFWILGDVFIGRYY 379
            ::.|||.|.|.:|||.:.|.|..|::. .:..|.:||||.|..||     ...|||||||||.||
  Rat   326 KVSSLPIITFKLGGQNYELHPEKYILK-VSQAGKTICLSGFMGMDIPPPSGPLWILGDVFIGCYY 389

  Fly   380 TAFDAGQRRIGFAPAA 395
            |.||....|:|||.||
  Rat   390 TVFDREYNRVGFAKAA 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	Asp	80..394	CDD:394983	143/326 (44%)
Ctsd	NP_599161.2	A1_Propeptide	23..49	CDD:462326	7/28 (25%)
		Cathepsin_D2	73..403	CDD:133157	144/330 (44%)