Protein Alignment CG5863 and Ctsd

DIOPT Version :10

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_034113.1
• Gene: Ctsd / 13033
• MGIID: 88562
• Length: 410
• Species: Mus musculus
• Alignment Length: 394
• Identity: 157/394 - (39%)
• Similarity: 223/394 - (56%)
• Gaps: 31/394 - (7%)

  Fly    25 LIRIPMQFQASFMASRRQHRAGRSSL--------LAKYNVVGGQEVTSRNGGATETLDNRLNLEY 81
            :||||::   .|.:.||.......|:        :.||::....:.|.   ..:|.|.|.|:.:|
Mouse    21 IIRIPLR---KFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTE---PVSELLKNYLDAQY 79

  Fly    82 AGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPDGRRFSIAYGT 146
            .|.|.||:|.|.|.::|||||:||||||..|....:||..||:||:..|||:|.:|..|.|.||:
Mouse    80 YGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGS 144

  Fly   147 GSLSGRLAQDTVAI---------GQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAELGI 202
            |||||.|:||||::         ..:.|:.|.||.||.:||..||...|.||:|:|:..|:...:
Mouse   145 GSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNV 209

  Fly   203 KPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQFPLDV 267
            .|:|:::..|:|||:.:|||||.|:...:.||||:.||.|...:.|.|:|:.:|...|||..:|.
Mouse   210 LPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQ 274

  Fly   268 IEVAG--TRINQNRQAIADTGTSLLAAPPREYLIINSLLGGLPTSNNEYLLNCSEIDSLPEIVFI 330
            :||..  |......:||.|||||||..|..|...:...:|.:|....||::.|.::.|||.:...
Mouse   275 LEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQGEYMIPCEKVSSLPTVYLK 339

  Fly   331 IGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD-----AEFWILGDVFIGRYYTAFDAGQRRIG 390
            :||:.:.|.|..|::. .:..|.:||||.|..||     ...|||||||||.|||.||....|:|
Mouse   340 LGGKNYELHPDKYILK-VSQGGKTICLSGFMGMDIPPPSGPLWILGDVFIGSYYTVFDRDNNRVG 403

  Fly   391 FAPA 394
            ||.|
Mouse   404 FANA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	Asp	80..394	CDD:394983	141/329 (43%)
Ctsd	NP_034113.1	A1_Propeptide	23..49	CDD:462326	7/28 (25%)
		Cathepsin_D2	73..405	CDD:133157	141/332 (42%)