Protein Alignment CG5863 and Pgc

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_080249.2
• Gene: Pgc / 109820
• MGIID: 98909
• Length: 392
• Species: Mus musculus
• Alignment Length: 403
• Identity: 144/403 - (35%)
• Similarity: 216/403 - (53%)
• Gaps: 30/403 - (7%)

  Fly     8 WLSLWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSRNGGATET 72
            |:.:.:|||  ...:..|||:|::...|...:.:: :......|..:....||:......|....
Mouse     3 WMVVALLCL--PLLEAALIRVPLKKMKSIRETMKE-QGVLKDFLKNHKYDPGQKYHFGKFGDYSV 64

  Fly    73 LDN---RLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFV 134
            |..   .::..|.|.||||:|.|.|.:||||||:||||.|..|  :|.||..|.|||.|.|||:.
Mouse    65 LYEPMAYMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYC--QSEACTTHTRYNPSKSSTYY 127

  Fly   135 PDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPIAE 199
            ..|:.||:.||||||:|....||:.:..:.|.||.||::.:|||..||...|.||:||.:..::.
Mouse   128 TQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPGLSS 192

  Fly   200 LGIKPLFESMCDQQLVDECVFSFYLKRNGSER--KGGELLFGGVDKTKFSGSLTYVPLTHAGYWQ 262
            .|.....:.|..:..:.:.:|..||   ||::  .||:::|||||:..::|.||::|:|...|||
Mouse   193 GGATTALQGMLGEGALSQPLFGVYL---GSQQGSNGGQIVFGGVDENLYTGELTWIPVTQELYWQ 254

  Fly   263 FPLDVI----EVAGTRINQNRQAIADTGTSLLAAPPREYLIINSLL---GGLPTSNNEYLLNCSE 320
            ..:|..    :.:|...:...|.|.|||||||.. |.:||  |.||   |.......:|.::|..
Mouse   255 ITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVM-PAQYL--NELLQTIGAQEGEYGQYFVSCDS 316

  Fly   321 IDSLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMDAE----FWILGDVFIGRYYTA 381
            :.|||.:.|::.|.:|.|.|..|::   .::||.:.......::||    .|||||||:..||..
Mouse   317 VSSLPTLTFVLNGVQFPLSPSSYII---QEEGSCMVGLESLSLNAESGQPLWILGDVFLRSYYAV 378

  Fly   382 FDAGQRRIGFAPA 394
            ||.|..|:|.||:
Mouse   379 FDMGNNRVGLAPS 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	129/336 (38%)
		Asp	80..394	CDD:278455	129/326 (40%)
Pgc	NP_080249.2	A1_Propeptide	18..46	CDD:285240	6/28 (21%)
		pepsin_retropepsin_like	73..391	CDD:299705	129/328 (39%)
		Asp	75..390	CDD:278455	128/325 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2599
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1456
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.880