DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5863 and LOC100489782

DIOPT Version :9

Sequence 1:	NP_650623.1	Gene:	CG5863 / 42096	FlyBaseID:	FBgn0038507	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_002933028.1	Gene:	LOC100489782 / 100489782	-ID:	-	Length:	383	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	145/404 - (35%)
Similarity:	218/404 - (53%)	Gaps:	39/404 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WLSLWILCLFWAKCQGQLIRIPMQFQASFMASRRQHRAGRSSLLAKYNVVGGQEVTSR-NGGATE 71
            :|.|.::||   :....|:|:|:....|.    ||:.| .:.:|.||......:::|| .|.|..
Frog     3 FLILILVCL---QLSEGLVRVPLMKSKSI----RQNMA-EAGVLDKYLQTHKIDLSSRYRGYAVV 59

  Fly    72 TLDNRLNLEYAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSVACHHHHRYNASASSTFVPD 136
            |.....:..|.||||||:|.|.|.:||||||:||||||:.|  :|.||.:|:.:..|.|||:..:
Frog    60 TESMYFDTYYYGPISIGTPPQNFLVLFDTGSSNLWVPSSYC--QSSACTNHNVFKPSQSSTYSSN 122

  Fly   137 GRRFSIAYGTG----SLSGRLAQDTVAIGQLVVQNQTFGMATHEPGPTFVDTNFAGIVGLGFRPI 197
            |::|::.||.|    |::|....|||:|..:.:.||.||:...||...|..:.|.||:||.:..:
Frog   123 GQKFTMGYGGGNVASSVTGLFGYDTVSIQGISITNQEFGLTITEPTSNFYYSPFDGILGLAYPGL 187

  Fly   198 AELGIKPLFESMCDQQLVDECVFSFYLKRNGSERKGGELLFGGVDKTKFSGSLTYVPLTHAGYWQ 262
            :..|.:.:.:.|..:.|::..:||.||   ||:  .||::|||||...::|.:.:.||:...|||
Frog   188 SVEGAQTVLQGMMQENLLNPSMFSIYL---GSQ--SGEIIFGGVDSNLYTGQIYWAPLSQELYWQ 247

  Fly   263 FPLDVIEVAGTR---INQNRQAIADTGTSLLAAPPREYLIINSLLG--GLPTSNNEYLLNCSEID 322
            ..|....:.|..   .:|..|||.||||:.|.. |:.||  ..||.  |:.|.|..|.:||:.:.
Frog   248 VALQEFSINGQATGWCSQGCQAIVDTGTTQLNI-PQTYL--TKLLPYLGIQTQNGGYYVNCNNLQ 309

  Fly   323 SLPEIVFIIGGQRFGLQPRDYVMSATNDDGSSICLSAFTLMD------AEFWILGDVFIGRYYTA 381
            :||.:.|.|.|..|.|.|..|::..     :..|.:.|..:.      ...|||||||:.:||:.
Frog   310 NLPTLSFTINGVSFPLPPSAYIIQE-----NGYCYANFLNLSLPAQNGQPLWILGDVFLRQYYSV 369

  Fly   382 FDAGQRRIGFAPAA 395
            ||.|..:||||..|
Frog   370 FDYGNNQIGFASLA 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	124/335 (37%)
CG5863	NP_650623.1	Asp	80..394	CDD:278455	125/328 (38%)
LOC100489782	XP_002933028.1	A1_Propeptide	17..45	CDD:369623	10/32 (31%)
LOC100489782	XP_002933028.1	pepsin_retropepsin_like	66..381	CDD:386101	124/329 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930