Protein Alignment CG5863 and bace2

DIOPT Version :9

• Sequence 1: NP_650623.1
• Gene: CG5863 / 42096
• FlyBaseID: FBgn0038507
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001135590.1
• Gene: bace2 / 100216145
• XenbaseID: XB-GENE-1014090
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 378
• Identity: 97/378 - (25%)
• Similarity: 168/378 - (44%)
• Gaps: 56/378 - (14%)

  Fly    59 GQEVTSRNGGATETLDNRLNLE------YAGPISIGSPGQPFNMLFDTGSANLWVPSAECSPKSV 117
            |..:.|..||.........|||      |...:.||:|.|..|:|.||||:|..|..| .:|...
 Frog    47 GLLLASDPGGQINFFSMVNNLEGDSGRGYYLELLIGTPPQKMNILVDTGSSNFAVAGA-LNPDIT 110

  Fly   118 ACHHHHRYNASASSTFVPDGRRFSIAYGTGSLSGRLAQDTVAIGQLVVQNQTF--GMATHEPGPT 180
            ..     :::..|:::.|...:.::.|..||.:|.|.:|.:::.:.|  |.||  .:|:......
 Frog   111 TF-----FDSKLSTSYEPLNTQVTVRYTQGSWTGLLGKDVISMPKGV--NGTFLINIASIFQSEN 168

  Fly   181 FV--DTNFAGIVGLGFRPIAE--LGIKPLFESMCDQQLVDECVFSFYLKRNGSERKG-----GEL 236
            |.  :.|:.||:||.:..:|:  ..::|.|:|:..|:.:.. :||..:...|....|     |.|
 Frog   169 FFLPNINWQGILGLAYSTLAKPSSSVEPFFDSLVQQENIPN-IFSMQMCGAGQPSPGIGINAGSL 232

  Fly   237 LFGGVDKTKFSGSLTYVPLTHAGYWQFPLDVIEVAGTRIN------QNRQAIADTGTSLLAAPPR 295
            :.||::.:.:.|.:.|.|:|...|:|..:...||.|..:|      .:.:||.|:||:||..|.:
 Frog   233 VLGGIEPSLYQGDIWYTPITEEWYYQVEVLKFEVGGQNLNLDCTVYNSDKAIVDSGTTLLRLPDK 297

  Fly   296 EYLIINSLLGGL-PTS-----NNEY----LLNC-----SEIDSLPEIVFIIGGQ------RFGLQ 339
               :.|:::..: .||     |.|:    .|.|     ...:..|:|...:...      |..|:
 Frog   298 ---VFNAMVDAIVQTSLIQNFNAEFWAGLQLACWDKTQDPWNYFPDISIYLRDTNSSRSFRLTLK 359

  Fly   340 PRDYVMSATNDDGSSICLSAFTLMDAEFWILGDVFIGRYYTAFDAGQRRIGFA 392
            |:.|:.|......|..|........|...::|...:..:|..||..::|:|||
 Frog   360 PQLYIQSVLTFQESLNCFRFGISQSASALVIGATVMEGFYVIFDRAEKRVGFA 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5863	NP_650623.1	pepsin_retropepsin_like	71..392	CDD:299705	91/364 (25%)
		Asp	80..394	CDD:278455	91/357 (25%)
bace2	NP_001135590.1	beta_secretase_like	72..433	CDD:133140	90/353 (25%)
		Asp	75..412	CDD:278455	88/348 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910