Protein Alignment CG5860 and MKC7

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_010428.3
• Gene: MKC7 / 851722
• SGDID: S000002551
• Length: 596
• Species: Saccharomyces cerevisiae
• Alignment Length: 487
• Identity: 106/487 - (21%)
• Similarity: 188/487 - (38%)
• Gaps: 138/487 - (28%)

  Fly     2 LRVLCF----LLAFLSLVFA-TQKILKVP---LYVRRSFNE---SEVFLARSATEGGETL----- 50
            |.||.|    ||...|:|.| ......:|   :||:.:|.:   |....|...|:|...|
Yeast     3 LSVLTFVVDALLVCSSIVDAGVTDFPSLPSNEVYVKMNFQKKYGSSFENALDDTKGRTRLMTRDD 67

  Fly    51 QLQLLLQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSA-------------- 101
            ..:|:..|:.|..|...:.:|.|.|..||:.|||||:.|:...:.|..::.
Yeast    68 DYELVELTNQNSFYSVELDIGTPPQKVTVLVDTGSSDLWVTGSDNPYCSTKKKDTTGSSFKQVNK 132

  Fly   102 ----------------------------------------CQNHRKYNSSRSSSYIPDGRNFTLR 126
                                                    |..:..:|:|:||::..:...|::.
Yeast   133 DALASVVESVFTEISYDTTIVTSEATATFDSTASTSQLIDCATYGTFNTSKSSTFNSNNTEFSIA 197

  Fly   127 YGSGMVVGYLSKDTMHIAGAELPHFTFG-ESLFLQHFAFSSVKF------DGLVG-LGLGVLSWS 183
            ||          ||...:|      |:| :.|.|.....:.:.|      :..|| ||:|:....
Yeast   198 YG----------DTTFASG------TWGHDQLSLNDLNITGLSFAVANETNSTVGVLGIGLPGLE 246

  Fly   184 NTTPFLELLCAQR---------------LLEKCVFSVYLRRDPRE---IVFGGFDESKFEGKLHY 230
            :|...:.|...|:               :::...:|::......:   |:||..|..|:.|.|:.
Yeast   247 STYSGVSLSSVQKSYTYNNFPMVLKNSGVIKSTAYSLFANDSDSKHGTILFGAVDHGKYAGDLYT 311

  Fly   231 VPV--SQWHTW-----SLQISKSSVGTKQIGGKSN-----------AILDTGTSLVLVPQQTYHN 277
            :|:  :..|..     ..|::...:||.: |.|.:           .:||:||::..:|.:....
Yeast   312 IPIINTLQHRGYKDPIQFQVTLQGLGTSK-GDKEDNLTTLTTTKIPVLLDSGTTISYMPTELVKM 375

  Fly   278 LLNTLSAKLQN--GYFVVACKSGSLPNINILIGDKVFPLTS--SDYIMEVLLD-RKPACVLAIAP 337
            |.:.:.|...:  ||:::.|........:|:.....|.|::  ||:  :::.| |...|:|.|||
Yeast   376 LADQVGATYSSAYGYYIMDCIKEMEEESSIIFDFGGFYLSNWLSDF--QLVTDSRSNICILGIAP 438

  Fly   338 INRGFWVLGDIFLRRYYTVFDATEKRIGLAKA 369
            .:....:|||.||...|.|:|.....|.:|:|
Yeast   439 QSDPTIILGDNFLANTYVVYDLDNMEISMAQA 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	84/409 (21%)
		Asp	63..369	CDD:278455	84/408 (21%)
MKC7	NP_010428.3	SAP_like	79..470	CDD:133141	84/409 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1428
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.730