Protein Alignment CG5860 and YPS1

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_013221.1
• Gene: YPS1 / 850811
• SGDID: S000004110
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 493
• Identity: 117/493 - (23%)
• Similarity: 186/493 - (37%)
• Gaps: 155/493 - (31%)

  Fly    10 AFLSLVFATQ------------------KILKVPLYVRRSFNES----------EVFLARSATEG 46
            |.||.:||:|                  |.:|:|.:  :.:.:|          ||.|.:.| :|
Yeast     9 AVLSSLFASQVLGKIIPAANKRDDDSNSKFVKLPFH--KLYGDSLENVGSDKKPEVRLLKRA-DG 70

  Fly    47 GETLQLQLLLQTHNNMEYYGT-IAMGNPRQNFTVIFDTGSSNTWLPSVNCP--MSNSACQNHRKY 108
            .|.:.:.      |...:|.. :.:|.|.||.||:.|||||:.|:...:.|  .|||...:.|:.
Yeast    71 YEEIIIT------NQQSFYSVDLEVGTPPQNVTVLVDTGSSDLWIMGSDNPYCSSNSMGSSRRRV 129

  Fly   109 -----NSSRSSSYIPDGRNFTLRYGSGMVVGYLSKD--------TMHIAGAEL-----PHFTF-- 153
                 :||...|.|.|...|....|:|..:|..:..        |..:..:|.     .:.||
Yeast   130 IDKRDDSSSGGSLINDINPFGWLTGTGSAIGPTATGLGGGSGTATQSVPASEATMDCQQYGTFST 194

  Fly   154 -GESLFLQHFAFSSVKF-DG------------------LVGLGLGVLSWSNTT--------PFLE 190
             |.|.|..:..:.|:.: ||                  :.||...|.:.:|:|        |.||
Yeast   195 SGSSTFRSNNTYFSISYGDGTFASGTFGTDVLDLSDLNVTGLSFAVANETNSTMGVLGIGLPELE 259

  Fly   191 ----------------------LLCAQRLLEKCVFSVYLRRDPR---EIVFGGFDESKFEGKLHY 230
                                  :|.....::...:|:||.....   .|:||..|.||:.|.|:.
Yeast   260 VTYSGSTASHSGKAYKYDNFPIVLKNSGAIKSNTYSLYLNDSDAMHGTILFGAVDHSKYTGTLYT 324

  Fly   231 VPVSQWHTWS-------LQISKSSVGTKQIGGKSN---------AILDTGTSLVLVPQQTYHNLL 279
            :|:....:.|       ..::.:.:|... .|.||         |:||:||:|..:||.....:.
Yeast   325 IPIVNTLSASGFSSPIQFDVTINGIGISD-SGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMIA 388

  Fly   280 NTLSAKLQN--GYFVVACKSGSLPNINILIGDKVF---------PLTSSDYIMEVLLDRKPACVL 333
            ..|.|:..:  ||:|:.|.|.....|       ||         ||:|      .:|.....|:|
Yeast   389 TELGAQYSSRIGYYVLDCPSDDSMEI-------VFDFGGFHINAPLSS------FILSTGTTCLL 440

  Fly   334 AIAPINRGF-WVLGDIFLRRYYTVFDATEKRIGLAKAK 370
            .|.|.:... .:|||.||...|.|:|.....|.:|:|:
Yeast   441 GIIPTSDDTGTILGDSFLTNAYVVYDLENLEISMAQAR 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	98/410 (24%)
		Asp	63..369	CDD:278455	99/409 (24%)
YPS1	NP_013221.1	SAP_like	81..477	CDD:133141	99/409 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.700