Protein Alignment CG5860 and bace1

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001072485.1
• Gene: bace1 / 779940
• XenbaseID: XB-GENE-5787150
• Length: 502
• Species: Xenopus tropicalis
• Alignment Length: 431
• Identity: 93/431 - (21%)
• Similarity: 168/431 - (38%)
• Gaps: 93/431 - (21%)

  Fly     4 VLCFLLAFLSLVFATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLL-----LQTHNNME 63
            :|..|..||.:  ..|..:|:||...........:.|:.:.|.|..|....|     |:..:...
 Frog    13 LLVLLPCFLPV--TGQVAIKLPLKNCPGTCSPMAYRAKRSAEKGMELDTNFLDMIDNLRGKSGQG 75

  Fly    64 YYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSAC--QNHRKYNSSRSSSYIPDGRNFTLR 126
            ||..:.:|.|.|...::.||||||..:.:...|......  |:.|.|...|...|:|
 Frog    76 YYVEMRVGTPPQTLNILVDTGSSNFAVGAAPHPFLKRYYHRQHSRTYRDVRRGVYVP-------- 132

  Fly   127 YGSGMVVGYLSKDTMHI-------AGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSWSN 184
            |..|...|.|..|.:.|       ..|.:...|..:..|:     :...::|::||....::..:
 Frog   133 YTQGKWEGELGTDLVTIPHGPNVTVTANIAAITDSDKFFI-----NGSNWEGILGLAYAEIARPD 192

  Fly   185 TT--PFLELLCAQRLLEKCVFSVYL--------RRDPR-----EIVFGGFDESKFEGKLHYVPV- 233
            .|  ||.:.|..|..:.. :||:.|        ..|..     .:|.||.|.|.:.|.:.|.|:
 Frog   193 DTLEPFFDSLVKQTRVPN-IFSLQLCGTGFHFNESDTSASVGGSMVIGGIDPSLYIGSIWYTPIR 256

  Fly   234 SQWHTWSLQISKSSVGTKQIG------GKSNAILDTGTSLVLVPQQTYHNLLNTLSA-----KLQ 287
            .:|: :.:.|.|..:..:.:.      ....:|:|:||:.:.:|::.:...:.::.|     |..
 Frog   257 KEWY-YEVIIVKIEINGQDLHMDCKEYNYDKSIVDSGTTNLRLPKRVFDAAVKSIKAASSTEKFP 320

  Fly   288 NGYF----VVACKSGSLPNINILIGDKVFPLTSSDYIM----------------------EVLLD 326
            :|::    :|..:.|:.|       ..:||:.|. |:|                      ::...
 Frog   321 DGFWLGEQLVCWQEGTTP-------WHIFPVISL-YLMGEVANQSFKITILPQQYLRPVEDIATA 377

  Fly   327 RKPACVLAIAPINRGFWVLGDIFLRRYYTVFDATEKRIGLA 367
            ::.....|::....| .|:|.:.:..:|.|||...||||.|
 Frog   378 QEDCYKFAVSQSTTG-TVMGAVIMEGFYVVFDRANKRIGFA 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	79/369 (21%)
		Asp	63..369	CDD:278455	79/367 (22%)
bace1	NP_001072485.1	beta_secretase_like	73..438	CDD:133140	79/369 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910