Protein Alignment CG5860 and REN

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_000528.1
• Gene: REN / 5972
• HGNCID: 9958
• Length: 406
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 125/366 - (34%)
• Similarity: 190/366 - (51%)
• Gaps: 24/366 - (6%)

  Fly    28 VRRSFNESEVFLARSATEGGETLQ--------LQLLLQTHNNMEYYGTIAMGNPRQNFTVIFDTG 84
            :|.|..|..|.:||...|..:.::        ..::|..:.:.:|||.|.:|.|.|.|.|:||||
Human    42 IRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTG 106

  Fly    85 SSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRNFTLRYGSGMVVGYLSKDTMHIAGAELP 149
            |||.|:||..|....:||..|:.:::|.||||..:|...||||.:|.|.|:||:|.:.:.|..:.
Human   107 SSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVT 171

  Fly   150 HFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPR-- 212
            .. |||...:....|...:|||:||:|....:....||..:.:.:|.:|::.|||.|..||..
Human   172 QM-FGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENS 235

  Fly   213 -----EIVFGGFDESKFEGKLHYVPVSQWHTWSLQISKSSVGTKQIGGKSN--AILDTGTSLVLV 270
                 :||.||.|...:||..||:.:.:...|.:|:...|||:..:..:..  |::|||.|.:..
Human   236 QSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG 300

  Fly   271 PQQTYHNLLNTLSAKLQNGYFVVACKSG-SLPNINILIGDKVFPLTSSDYIMEVLLDRKPACVLA 334
            ...:...|:..|.||.:...:||.|..| :||:|:..:|.|.:.|||:||:.:.....|..|.||
Human   301 STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLA 365

  Fly   335 -----IAPINRGFWVLGDIFLRRYYTVFDATEKRIGLAKAK 370
                 |.|.....|.||..|:|::||.||....|||.|.|:
Human   366 IHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	115/321 (36%)
		Asp	63..369	CDD:278455	116/320 (36%)
REN	NP_000528.1	A1_Propeptide	33..>51	CDD:311771	3/8 (38%)
		renin_like	78..405	CDD:133154	117/327 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.880