Protein Alignment CG5860 and Pga5

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_067428.2
• Gene: Pga5 / 58803
• MGIID: 1915935
• Length: 387
• Species: Mus musculus
• Alignment Length: 392
• Identity: 132/392 - (33%)
• Similarity: 202/392 - (51%)
• Gaps: 46/392 - (11%)

  Fly    12 LSLVFATQKILKVPLY----VRRSFNESEVFLARSATEGGETLQLQLLLQTHNN----------- 61
            |.||..::.::|:||.    :|.:..||:|.  :...|.....:..:||:...|
Mouse     7 LGLVALSECLVKIPLMKIKSMRENLRESQVL--KDYLEKYPRSRAHVLLEQRRNPAVTYEPMRNY 69

  Fly    62 --MEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRNFT 124
              :.|.|.|::|.|.|.|.|:.|||||..|:||:.|  |:.||.:|:.:|..|||:::..||...
Mouse    70 LDLVYIGIISIGTPPQEFRVVLDTGSSVLWVPSIYC--SSPACAHHKAFNPLRSSTFLVSGRPVN 132

  Fly   125 LRYGSGMVVGYLSKDTMHIAGAELPHFTFGESL-----FLQHFAFSSVKFDGLVGLGLGVLSWSN 184
            :.||||.:.|:|:.||:.|....:....||.||     |:::     ..|||::|||...|....
Mouse   133 VAYGSGEMSGFLAYDTVRIGDLTVVAQAFGLSLEEPGIFMEY-----AVFDGILGLGYPNLGLQG 192

  Fly   185 TTPFLELLCAQRLLEKCVFSVYLRRDPRE---IVFGGFDESKFEGKLHYVPVSQWHTWSLQISKS 246
            .||..:.|..|.|:.:.:|:.||.....:   ::.||.|.|.:.|:||:||||:...|.|.:...
Mouse   193 ITPVFDNLWLQGLIPQNLFAFYLSSKDEKGSMLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSI 257

  Fly   247 SVGTKQIG--GKSNAILDTGTSLVLVPQQTYHNLLNTLSAKLQ-NGYFVVACKS-GSLPNINILI 307
            |:..:.|.  |....|:||||||:..|:.:..|:.|.:.||.. :|.:.:.|.: .:||:|...|
Mouse   258 SMNGEVIACDGGCQGIMDTGTSLLTGPRSSIVNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTI 322

  Fly   308 GDKVFPLTSSDYIMEVLLDRKPACVLAIA-----PINRGFWVLGDIFLRRYYTVFDATEKRIGLA 367
            |...:|:.:|.||.:   ||...|.....     |.:...|||||:|||.|:||||....|||||
Mouse   323 GSVTYPVPASAYIRK---DRSHNCRSNFEEGMDDPSDPEMWVLGDVFLRLYFTVFDRANNRIGLA 384

  Fly   368 KA 369
            .|
Mouse   385 PA 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	117/336 (35%)
		Asp	63..369	CDD:278455	117/322 (36%)
Pga5	NP_067428.2	A1_Propeptide	16..44	CDD:285240	8/29 (28%)
		pepsin_retropepsin_like	64..385	CDD:299705	116/330 (35%)
		Asp	74..386	CDD:278455	117/321 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920