DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5860 and sxa1

DIOPT Version :9

Sequence 1:	NP_650622.1	Gene:	CG5860 / 42095	FlyBaseID:	FBgn0038506	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001342952.1	Gene:	sxa1 / 3361468	PomBaseID:	SPAC26A3.01	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	416	Identity:	97/416 - (23%)
Similarity:	168/416 - (40%)	Gaps:	100/416 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 YVRRSFNESEVFLARSATEGGETLQLQLLLQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLP 91
            :|.|....::|...|.:: |...|.|:..    :...|:..:.:|:..:.:::..||||..||:.
pombe    44 HVARKLERTKVLNKRDSS-GYPVLDLEYT----DAGGYFANLTLGSNERVYSLTLDTGSPYTWVT 103

  Fly    92 SVN----------------------CPMSNSACQNH----------RKYNSSRSSSYIPDGRNFT 124
            :.|                      ..:..:||.|:          |:.|||........|.|.|
pombe   104 AKNITALSASEIWSDTDGVDAGRSTSDIRTNACTNYTCFDYSSTTARRTNSSTIGFLASYGDNTT 168

  Fly   125 LRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKF-DGLVGLGL-----GVLSWS 183
                   |:||...|..:.||..||.|.||  |..:.:..|.:.. .|::||.:     |:.|..
pombe   169 -------VLGYNMVDNAYFAGLTLPGFEFG--LATREYDSSQISVTPGIIGLSVAMTITGISSDD 224

  Fly   184 NTTPF-----LELLCAQRLLEKCVFSVYLRRDPREIVFGGFDESKFEGKLHYVPVSQW------- 236
            ....|     ::.|.:..:::...|.:||..|..|::|||:|::|..|.:|:|.:|..
pombe   225 KVVAFTPPTIVDQLVSANVIDTPAFGIYLNEDVGELIFGGYDKAKINGSVHWVNISSSDDSTFYS 289

  Fly   237 ----------HTWSLQISKSSVGTKQIGGKSNAILDTGTSLVLVPQQTYHNLLNTLSAKL-QNGY 290
                      .|.|..:..|...:|.|...:...|||||..:.:|:.|..::.:.....: :.||
pombe   290 VNLESITVTNSTSSNNVQSSKRSSKDIEVNTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEYGY 354

  Fly   291 FVVACKS-----------GSLPNINILIGDKVF---PLTSSDYIMEVLLDRKPACVLAIAPINRG 341
            .|:.|.|           ||..:.::.:.|.|.   ..||.|           .|.||:...:..
pombe   355 VVIYCDSFSDSDYISFNFGSDADFHVSVNDLVIYRQESTSGD-----------ICYLALFEGDTS 408

  Fly   342 FWVLGDIFLRRYYTVFDATEKRIGLA 367
            .::||..||:..|:::|...::||||
pombe   409 SYLLGQYFLQYVYSIYDWDAQKIGLA 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	90/382 (24%)
CG5860	NP_650622.1	Asp	63..369	CDD:278455	90/380 (24%)
sxa1	NP_001342952.1	Asp	75..436	CDD:306525	90/380 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		otm47413
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1428
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.950