Protein Alignment CG5860 and Bace2

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001002802.1
• Gene: Bace2 / 288227
• RGDID: 1303241
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 365
• Identity: 86/365 - (23%)
• Similarity: 159/365 - (43%)
• Gaps: 72/365 - (19%)

  Fly    56 LQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDG 120
            ||..:...||..:.:|.|.|...::.||||||  ......|  :|....:  ::|..||:|...|
  Rat    80 LQGDSGRGYYLEMLIGTPPQKVRILVDTGSSN--FAVAGAP--HSYIDTY--FDSESSSTYHSKG 138

  Fly   121 RNFTLRYGSGMVVGYLSKDTMHIAGAELPHF-----TFGESLFLQHFAFSSVKFDGLVGLGLGVL 180
            ...|::|..|...|::.:|.:.|.......|     |..||   ::|....:|::|::||....|
  Rat   139 FEVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFES---ENFFLPGIKWNGILGLAYAAL 200

  Fly   181 S--WSNTTPFLELLCAQRLLEKCVFSVYL----------RRDPREIVFGGFDESKFEGKLHYVPV 233
            :  .|:...|.:.|.||..:.. :||:.:          ..:...:|.||.:.|.::|.:.|.|:
  Rat   201 AKPSSSLETFFDSLVAQAKIPD-IFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPI 264

  Fly   234 SQWHTWSLQISKSSVGTKQIG------GKSNAILDTGTSLVLVPQQTYHNLL-----NTLSAKLQ 287
            .:...:.::|.|..:|.:.:.      ....||:|:||:|:.:||:.:..::     .:|..:..
  Rat   265 KEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFS 329

  Fly   288 NGYFV---VACKSGS------LPNINILIGDKVFPLTSSDYIMEVLLDRKPACVLAIAP-INRGF 342
            :|::.   :||.:.|      .|.|:|.:.|:   ..|..:.:.:|..      |.|.| :..||
  Rat   330 DGFWTGAQLACWTNSETPWAYFPKISIYLRDE---NASRSFRITILPQ------LYIQPMMGAGF 385

  Fly   343 ---------------WVLGDIFLRRYYTVFDATEKRIGLA 367
                           .|:|...:..:|.|||..::|:|.|
  Rat   386 NYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFA 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	84/360 (23%)
		Asp	63..369	CDD:278455	84/358 (23%)
Bace2	NP_001002802.1	beta_secretase_like	85..446	CDD:133140	84/360 (23%)
		Asp	88..425	CDD:278455	83/355 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900