Protein Alignment CG5860 and Ctse

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_006249810.1
• Gene: Ctse / 25424
• RGDID: 2446
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 136/405 - (33%)
• Similarity: 212/405 - (52%)
• Gaps: 49/405 - (12%)

  Fly     2 LRVLCFLLAFLSLVFATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLLLQTHN------ 60
            |.||..||..|.|..|...:.:|||...:|..:      :...:|    ||....::||
  Rat     4 LFVLLLLLLLLDLAQAQGVLHRVPLRRHQSLRK------KLRAQG----QLSDFWRSHNLDMIEF 58

  Fly    61 ------------------NMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRK 107
                              :|||:||:::|:|.|||||||||||||.|:|||.|  ::.||:.|..
  Rat    59 SESCNVDKGINEPLINYLDMEYFGTVSIGSPSQNFTVIFDTGSSNLWVPSVYC--TSPACKAHPV 121

  Fly   108 YNSSRSSSYIPDGRNFTLRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGL 172
            ::.|:||:|:..|.:|:::||:|.:.|.:..|.:.:.|..:....||||:......|.:.:|||:
  Rat   122 FHPSQSSTYMEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVEGQQFGESVKEPGQTFVNAEFDGI 186

  Fly   173 VGLGLGVLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPR-----EIVFGGFDESKFEGKLHYVP 232
            :|||...|:....||..:.:.||.|:...:|||||..||:     |:.|||:|.|.|.|.|:::|
  Rat   187 LGLGYPSLAVGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIP 251

  Fly   233 VSQWHTWSLQISKSSVGTKQI--GGKSNAILDTGTSLVLVPQQTYHNLLNTLSAKLQNGYFVVAC 295
            |::...|.:.:....||...:  .....||:||||||:..|.:....|...:.|...:|.:.|.|
  Rat   252 VTKQGYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPKKIKQLQEAIGATPMDGEYAVDC 316

  Fly   296 KS-GSLPNINILIGDKVFPLTSSDYIMEVLLDRKPAC-----VLAIAPINRGFWVLGDIFLRRYY 354
            .: ..:||:..||....:.|:.:.||:..|:|....|     .|.|.|.....|:|||:|:|::|
  Rat   317 ATLNMMPNVTFLINGVSYTLSPTAYILPDLVDGMQFCGSGFQGLDIQPPAGPLWILGDVFIRKFY 381

  Fly   355 TVFDATEKRIGLAKA 369
            :|||....::|||.|
  Rat   382 SVFDRGNNQVGLAPA 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	117/319 (37%)
		Asp	63..369	CDD:278455	117/318 (37%)
Ctse	XP_006249810.1	A1_Propeptide	23..51	CDD:285240	7/37 (19%)
		Asp	79..396	CDD:278455	117/318 (37%)
		pepsin_retropepsin_like	80..395	CDD:299705	115/316 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850