Protein Alignment CG5860 and Ren1

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_112469.1
• Gene: Ren1 / 19701
• MGIID: 97898
• Length: 402
• Species: Mus musculus
• Alignment Length: 383
• Identity: 134/383 - (34%)
• Similarity: 200/383 - (52%)
• Gaps: 26/383 - (6%)

  Fly    13 SLVFATQKILKVPL----YVRRSFNESEVFLARSATEGG--------ETLQLQLLLQTHNNMEYY 65
            ||...|....::||    .||....|..|.:.|.:.|.|        ..|...::|..:.|.:||
Mouse    21 SLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYY 85

  Fly    66 GTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGRNFTLRYGSG 130
            |.|.:|.|.|.|.|||||||:|.|:||..|.....||..|..|.||.||||:.:|.:||:.||||
Mouse    86 GEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSG 150

  Fly   131 MVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSWSNTTPFLELLCAQ 195
            .|.|:||:|::.:.|..:.. ||||...|....|...||||::|:|....:....||..:.:.:|
Mouse   151 RVKGFLSQDSVTVGGITVTQ-TFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQ 214

  Fly   196 RLLEKCVFSVYLRRDPR----EIVFGGFDESKFEGKLHYVPVSQWHTWSLQISKSSVGTKQIGGK 256
            .:|::.|||||..|...    |:|.||.|...::|..|||.:|:..:|.:.:...|||:..:..:
Mouse   215 GVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCE 279

  Fly   257 SN--AILDTGTSLVLVPQQTYHNLLNTLSAKLQN-GYFVVACKS-GSLPNINILIGDKVFPLTSS 317
            ..  .::|||:|.:..|..:...::..|.||.:. ..:||.|.. .:||:|:..:|.:.:.|:|:
Mouse   280 EGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSST 344

  Fly   318 DYIMEVLLDRKPACVLA-----IAPINRGFWVLGDIFLRRYYTVFDATEKRIGLAKAK 370
            ||:::....|...|.||     |.|.....||||..|:|::||.||....|||.|.|:
Mouse   345 DYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	118/319 (37%)
		Asp	63..369	CDD:278455	118/318 (37%)
Ren1	NP_112469.1	A1_Propeptide	29..54	CDD:285240	6/24 (25%)
		renin_like	76..401	CDD:133154	120/325 (37%)
		Asp	83..401	CDD:278455	118/318 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.870