Protein Alignment CG5860 and asp-12

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_505134.1
• Gene: asp-12 / 179210
• WormBaseID: WBGene00017678
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 106/399 - (26%)
• Similarity: 185/399 - (46%)
• Gaps: 51/399 - (12%)

  Fly     8 LLAFLSLV-FATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLLLQTHN----------- 60
            ||||:::: ..:..:::..|..|    ||.........|.|..:|.:..|:..|
 Worm     5 LLAFVAILGMCSATVVQHKLIYR----ESPKMQMMRRGEWGAYVQHKAALRDANPAVFASAPQNV 65

  Fly    61 ----NMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDGR 121
                ::||.|.|.:|.|.|.|.|:.||||:|.|:|..||   :..|:...:::||:|:::..:|:
 Worm    66 NDFGDVEYLGNITIGTPPQQFIVVLDTGSANLWVPGSNC---DGTCKGKSEFDSSKSTTFKKNGQ 127

  Fly   122 NFTLRYGSGMVVGYLSKDTMHIAGAE-----LPHFTFGESLFLQHFA--FSSVKFDGLVGLGLGV 179
            ::.::|.||...|.:..||:...||.     :|..|||   ...|.:  |.:...:|::||....
 Worm   128 SWQIQYESGSAKGIMGVDTVAFGGASEQQLLVPSTTFG---IASHISSNFKNDAAEGILGLAFTS 189

  Fly   180 LSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPRE-------IVFGGFDESKFEGKLHYVPVSQWH 237
            |:....||.|.....:::|::.:|:|:|......       ..:|..|.:.....:.|.|:|...
 Worm   190 LAVDGVTPPLINAINKKILDQPLFTVFLEHKGTAKNVGGGVFTYGAVDTTNCGPVIAYQPLSSAT 254

  Fly   238 TWSLQISKSSVGTKQIGGKSNAILDTGTSLVLVPQQTYHNLLNTLSAKL---QNGYFVVACKSGS 299
            .:........:|:.....||..|.|||:||:..|....:.....|.||.   .:.|: :.| |.|
 Worm   255 YYQFVADGFKLGSYSNNKKSQVISDTGSSLIGGPSAVINGFAQALGAKYHSDDDAYY-LPC-STS 317

  Fly   300 LPNINILIGDKVFPLTSSDYIMEVLLDRKPACVLAIAPINRG----FWVLGDIFLRRYYTVFDAT 360
            ...::|.||..|:.:...:||::|.:.  ..||.|....:.|    .|:.||.|:|:|..::|..
 Worm   318 KGTLDITIGGNVYSIEPVNYILDVGMG--DTCVFAAFSFDFGGFGPSWIFGDPFIRQYCNIYDIG 380

  Fly   361 EKRIGLAKA 369
            ::|||.||:
 Worm   381 QQRIGFAKS 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	91/327 (28%)
		Asp	63..369	CDD:278455	92/326 (28%)
asp-12	NP_505134.1	Asp	72..388	CDD:365818	91/325 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840