Protein Alignment CG5860 and Ctse

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_031825.2
• Gene: Ctse / 13034
• MGIID: 107361
• Length: 397
• Species: Mus musculus
• Alignment Length: 403
• Identity: 133/403 - (33%)
• Similarity: 209/403 - (51%)
• Gaps: 49/403 - (12%)

  Fly     4 VLCFLLAFLSLVFATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLLLQTHN-------- 60
            ::..||..|.|..|...:.:|||...:|..:      :...:|    ||....::||
Mouse     5 LVLLLLLLLDLAQAQGALHRVPLRRHQSLRK------KLRAQG----QLSEFWRSHNLDMTRLSE 59

  Fly    61 ----------------NMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYN 109
                            :|||:|||::|.|.|||||||||||||.|:|||.|  ::.||:.|..::
Mouse    60 SCNVYSSVNEPLINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYC--TSPACKAHPVFH 122

  Fly   110 SSRSSSYIPDGRNFTLRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVG 174
            .|:|.:|...|.:|:::||:|.:.|.:..|.:.:.|..:....||||:......|.:.:|||::|
Mouse   123 PSQSDTYTEVGNHFSIQYGTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTFVNAEFDGILG 187

  Fly   175 LGLGVLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPR-----EIVFGGFDESKFEGKLHYVPVS 234
            ||...|:....||..:.:.||.|:...:|||||..||:     |:.|||:|.|.|.|.|:::||:
Mouse   188 LGYPSLAAGGVTPVFDNMMAQNLVALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVT 252

  Fly   235 QWHTWSLQISKSSVGTKQI--GGKSNAILDTGTSLVLVPQQTYHNLLNTLSAKLQNGYFVVACKS 297
            :...|.:.:....||...:  .....||:||||||:..|......|...:.|...:|.:.|.|.:
Mouse   253 KQAYWQIALDGIQVGDTVMFCSEGCQAIVDTGTSLITGPPDKIKQLQEAIGATPIDGEYAVDCAT 317

  Fly   298 -GSLPNINILIGDKVFPLTSSDYIMEVLLDRKPAC-----VLAIAPINRGFWVLGDIFLRRYYTV 356
             .::||:..||.:..:.|..:|||:..|::....|     .|.|.|.....|:|||:|:|::|:|
Mouse   318 LDTMPNVTFLINEVSYTLNPTDYILPDLVEGMQFCGSGFQGLDIPPPAGPLWILGDVFIRQFYSV 382

  Fly   357 FDATEKRIGLAKA 369
            ||....::|||.|
Mouse   383 FDRGNNQVGLAPA 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	117/319 (37%)
		Asp	63..369	CDD:278455	117/318 (37%)
Ctse	NP_031825.2	A1_Propeptide	22..50	CDD:285240	7/37 (19%)
		Asp	78..395	CDD:278455	117/318 (37%)
		pepsin_retropepsin_like	79..394	CDD:299705	115/316 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S917
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.800