Protein Alignment CG5860 and Ctsd

DIOPT Version :9

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_034113.1
• Gene: Ctsd / 13033
• MGIID: 88562
• Length: 410
• Species: Mus musculus
• Alignment Length: 412
• Identity: 144/412 - (34%)
• Similarity: 217/412 - (52%)
• Gaps: 56/412 - (13%)

  Fly     4 VLCFLLAFL-SLVFATQKILKVPLYVRRSFNESEVFLARSATE-GGETLQLQL------------ 54
            ||..:|..| |..||   |:::||   |.|..    :.|:.|| ||....|.|
Mouse     6 VLLLILGLLASSSFA---IIRIPL---RKFTS----IRRTMTEVGGSVEDLILKGPITKYSMQSS 60

  Fly    55 ---------LLQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNS 110
                     ||:.:.:.:|||.|.:|.|.|.|||:|||||||.|:||::|.:.:.||..|.||||
Mouse    61 PKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNS 125

  Fly   111 SRSSSYIPDGRNFTLRYGSGMVVGYLSKDTMHI---------AGAELPHFTFGESLFLQHFAFSS 166
            .:||:|:.:|.:|.:.||||.:.||||:||:.:         .|.::....|||:.......|.:
Mouse   126 DKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVA 190

  Fly   167 VKFDGLVGLGLGVLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPR-----EIVFGGFDESKFEG 226
            .||||::|:|...:|.:|..|..:.|..|:|::|.:||.||.|||.     |::.||.|...:.|
Mouse   191 AKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHG 255

  Fly   227 KLHYVPVSQWHTWSLQISKSSVGTK--QIGGKSNAILDTGTSLVLVPQQTYHNLLNTLSA-KLQN 288
            :|.|:.|::...|.:.:.:..||.:  ...|...||:||||||::.|.:....|...:.| .|..
Mouse   256 ELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQ 320

  Fly   289 GYFVVAC-KSGSLPNINILIGDKVFPLTSSDYIMEVLLDRKPACV-----LAIAPINRGFWVLGD 347
            |.:::.| |..|||.:.:.:|.|.:.|....||::|....|..|:     :.|.|.:...|:|||
Mouse   321 GEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGD 385

  Fly   348 IFLRRYYTVFDATEKRIGLAKA 369
            :|:..||||||....|:|.|.|
Mouse   386 VFIGSYYTVFDRDNNRVGFANA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	121/329 (37%)
		Asp	63..369	CDD:278455	122/328 (37%)
Ctsd	NP_034113.1	A1_Propeptide	21..46	CDD:285240	10/31 (32%)
		Cathepsin_D2	73..405	CDD:133157	121/331 (37%)
		Asp	78..407	CDD:278455	122/328 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880