Protein Alignment CG5860 and Ctsd

DIOPT Version :10

• Sequence 1: NP_650622.1
• Gene: CG5860 / 42095
• FlyBaseID: FBgn0038506
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_034113.1
• Gene: Ctsd / 13033
• MGIID: 88562
• Length: 410
• Species: Mus musculus
• Alignment Length: 412
• Identity: 144/412 - (34%)
• Similarity: 217/412 - (52%)
• Gaps: 56/412 - (13%)

  Fly     4 VLCFLLAFL-SLVFATQKILKVPLYVRRSFNESEVFLARSATE-GGETLQLQL------------ 54
            ||..:|..| |..||   |:::||   |.|..    :.|:.|| ||....|.|
Mouse     6 VLLLILGLLASSSFA---IIRIPL---RKFTS----IRRTMTEVGGSVEDLILKGPITKYSMQSS 60

  Fly    55 ---------LLQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNS 110
                     ||:.:.:.:|||.|.:|.|.|.|||:|||||||.|:||::|.:.:.||..|.||||
Mouse    61 PKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNS 125

  Fly   111 SRSSSYIPDGRNFTLRYGSGMVVGYLSKDTMHI---------AGAELPHFTFGESLFLQHFAFSS 166
            .:||:|:.:|.:|.:.||||.:.||||:||:.:         .|.::....|||:.......|.:
Mouse   126 DKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVA 190

  Fly   167 VKFDGLVGLGLGVLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPR-----EIVFGGFDESKFEG 226
            .||||::|:|...:|.:|..|..:.|..|:|::|.:||.||.|||.     |::.||.|...:.|
Mouse   191 AKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHG 255

  Fly   227 KLHYVPVSQWHTWSLQISKSSVGTK--QIGGKSNAILDTGTSLVLVPQQTYHNLLNTLSA-KLQN 288
            :|.|:.|::...|.:.:.:..||.:  ...|...||:||||||::.|.:....|...:.| .|..
Mouse   256 ELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQ 320

  Fly   289 GYFVVAC-KSGSLPNINILIGDKVFPLTSSDYIMEVLLDRKPACV-----LAIAPINRGFWVLGD 347
            |.:::.| |..|||.:.:.:|.|.:.|....||::|....|..|:     :.|.|.:...|:|||
Mouse   321 GEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGMDIPPPSGPLWILGD 385

  Fly   348 IFLRRYYTVFDATEKRIGLAKA 369
            :|:..||||||....|:|.|.|
Mouse   386 VFIGSYYTVFDRDNNRVGFANA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	Asp	63..369	CDD:394983	122/328 (37%)
Ctsd	NP_034113.1	A1_Propeptide	23..49	CDD:462326	10/32 (31%)
		Cathepsin_D2	73..405	CDD:133157	121/331 (37%)