DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5860 and LOC100489782

DIOPT Version :9

Sequence 1:	NP_650622.1	Gene:	CG5860 / 42095	FlyBaseID:	FBgn0038506	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	XP_002933028.1	Gene:	LOC100489782 / 100489782	-ID:	-	Length:	383	Species:	Xenopus tropicalis

Alignment Length:	395	Identity:	131/395 - (33%)
Similarity:	198/395 - (50%)	Gaps:	51/395 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FLLAFLSLVFATQKILKVPLYVRRSFNESEVFLARSATEGGETLQLQLLLQTHN----------- 60
            ||:..|..:..::.:::|||...:|       :.::..|.|   .|...||||.
Frog     3 FLILILVCLQLSEGLVRVPLMKSKS-------IRQNMAEAG---VLDKYLQTHKIDLSSRYRGYA 57

  Fly    61 --------NMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYI 117
                    :..|||.|::|.|.|||.|:|||||||.|:||..|  .:|||.||..:..|:||:|.
Frog    58 VVTESMYFDTYYYGPISIGTPPQNFLVLFDTGSSNLWVPSSYC--QSSACTNHNVFKPSQSSTYS 120

  Fly   118 PDGRNFTLRYGSG----MVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLG 178
            .:|:.||:.||.|    .|.|....||:.|.|..:.:..||.::......|....|||::||...
Frog   121 SNGQKFTMGYGGGNVASSVTGLFGYDTVSIQGISITNQEFGLTITEPTSNFYYSPFDGILGLAYP 185

  Fly   179 VLSWSNTTPFLELLCAQRLLEKCVFSVYLRRDPREIVFGGFDESKFEGKLHYVPVSQWHTWSLQI 243
            .||.......|:.:..:.||...:||:||.....||:|||.|.:.:.|::::.|:||...|.:.:
Frog   186 GLSVEGAQTVLQGMMQENLLNPSMFSIYLGSQSGEIIFGGVDSNLYTGQIYWAPLSQELYWQVAL 250

  Fly   244 SKSSVGTKQIGGKS---NAILDTGTSLVLVPQQTYHNLLNTLSAKLQNGYFVVACKS-GSLPNIN 304
            .:.|:..:..|..|   .||:||||:.:.:||.....||..|..:.|||.:.|.|.: .:||.::
Frog   251 QEFSINGQATGWCSQGCQAIVDTGTTQLNIPQTYLTKLLPYLGIQTQNGGYYVNCNNLQNLPTLS 315

  Fly   305 ILIGDKVFPLTSSDYIMEVLLDRKPACV-----LAIAPINRG--FWVLGDIFLRRYYTVFDATEK 362
            ..|....|||..|.||::    ....|.     |:: |...|  .|:|||:|||:||:|||....
Frog   316 FTINGVSFPLPPSAYIIQ----ENGYCYANFLNLSL-PAQNGQPLWILGDVFLRQYYSVFDYGNN 375

  Fly   363 RIGLA 367
            :||.|
Frog   376 QIGFA 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	117/322 (36%)
CG5860	NP_650622.1	Asp	63..369	CDD:278455	117/320 (37%)
LOC100489782	XP_002933028.1	A1_Propeptide	17..45	CDD:369623	9/37 (24%)
LOC100489782	XP_002933028.1	pepsin_retropepsin_like	66..381	CDD:386101	117/322 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920