DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17283 and YPS7

DIOPT Version :9

Sequence 1:	NP_650621.1	Gene:	CG17283 / 42094	FlyBaseID:	FBgn0038505	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_010636.1	Gene:	YPS7 / 851950	SGDID:	S000002757	Length:	596	Species:	Saccharomyces cerevisiae

Alignment Length:	446	Identity:	98/446 - (21%)
Similarity:	166/446 - (37%)	Gaps:	125/446 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 FLANRYGFSFAKSSGTATLKNTANM---------------------EYTCKMNIGTPKQKFTVLP 167
            :|.:.:...||.:| ||....||..                     .|......|||.|:..:|.
Yeast    10 WLISTFQLEFATAS-TANTTTTAKSGTSSSTEEPFPVLAVGKDGRGNYYVNSTFGTPGQRQRLLV 73

  Fly   168 DTGSSNIWVPGPHCKSKACKKHKQY------HP------AKSSTYVKNGKSFAITYGSG-SVAGV 219
            |     |..|..:..|...:.|.:|      ||      :.||..|..|:.:.|::..| :|...
Yeast    74 D-----IIQPYINLVSGTSESHNEYSGVYHKHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCT 133

  Fly   220 LAKDTVRIAGLVVTNQTFAMTTK----------EPGTTFV---------TSNF--DGILGLGYR- 262
            |..|.:....:...|.:.|:.|.          ..|:..:         :|||  .|:|||..:
Yeast   134 LVTDDMNFTNVSSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSGKV 198

  Fly   263 ---SIAVDNVKTLVQN-----MCSEDVITSCKFAICMKGGGSS--------SRGGAIIFGSSNTS 311
               ..|:|:.:...|:     :...|:|.|..:::.:.|..|:        |..|.::.|..:.|
Yeast   199 TNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPS 263

  Fly   312 AYSGS----NSYTYT-PVTKK---GYWQFTLQDIYVGGTKVSGSVQ------------AIVDSGT 356
            .::|:    :...|. ||:..   ||....|..||:    ||.|.|            |::||.:
Yeast   264 LFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPIYI----VSNSGQSLNMTSKDFLSPALLDSTS 324

  Fly   357 SLITAPTAIYNKINKVIGCRATSSGECWM-KCAKKIPDFTFVIAGKKFVVKGNKMKLKVR----- 415
            |:...||:...:|...|......|.:.|: :|:  |.|....:.   |.::...:::.:|
Yeast   325 SVSYLPTSTIIQIAVQIAATYVESLDRWLVQCS--IADMGVSLG---FRLRELTIEIPLRDLLSS 384

  Fly   416 -----TN------RGRTVCISAVTEVPDEPV-ILGDAFIRHFCTEFDLANNRIGFA 459
                 ||      .|:..|...:....:..| |||:|||::.....||.:|.|..|
Yeast   385 TYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFIKNIYMAMDLEDNTIAIA 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	91/426 (21%)
CG17283	NP_650621.1	Asp	149..460	CDD:278455	90/400 (23%)
YPS7	NP_010636.1	pepsin_retropepsin_like	162..442	CDD:416259	64/288 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830