Protein Alignment CG17283 and ctsd

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_571785.2
• Gene: ctsd / 65225
• ZFINID: ZDB-GENE-010131-8
• Length: 398
• Species: Danio rerio
• Alignment Length: 388
• Identity: 141/388 - (36%)
• Similarity: 209/388 - (53%)
• Gaps: 28/388 - (7%)

  Fly    90 TESIVRSDSSYATLPLDFQQNFVRT-TDNLRSEKAFLAN----RYGFSFAKSSGTA--TLKNTAN 147
            :::|||       :||...:...|| :|:.||.:..:::    :|...|..|:...  ||||..:
Zfish    16 SDAIVR-------IPLKKFRTLRRTLSDSGRSLEELVSSSNSLKYNLGFPASNDPTPETLKNYLD 73

  Fly   148 MEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCK--SKACKKHKQYHPAKSSTYVKNGKSFAIT 210
            .:|..::.:|||.|.|||:.||||||:|||..||.  ..||..|.:|:..|||||||||..|||.
Zfish    74 AQYYGEIGLGTPVQTFTVVFDTGSSNLWVPSVHCSLTDIACLLHHKYNGGKSSTYVKNGTQFAIQ 138

  Fly   211 YGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGLGYRSIAVDNVKTLVQN 275
            |||||::|.|::||..|..:.|..|.|....|:||..|:.:.||||||:.|..||||.|..:...
Zfish   139 YGSGSLSGYLSQDTCTIGDIAVEKQIFGEAIKQPGVAFIAAKFDGILGMAYPRIAVDGVPPVFDM 203

  Fly   276 MCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQDIYVG 340
            |.|:..:....|:..:.....:..||.::.|.::...|:|  .:.|..::::.|||..:..:.:|
Zfish   204 MMSQKKVEKNVFSFYLNRNPDTQPGGELLLGGTDPKYYTG--DFNYVDISRQAYWQIHMDGMSIG 266

  Fly   341 G--TKVSGSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKCAK--KIPDFTFVIAGK 401
            .  :...|..:||||:||||||.|.|....:.|.||......||..:.|.|  .:|..:|.:.||
Zfish   267 SGLSLCKGGCEAIVDTGTSLITGPAAEVKALQKAIGAIPLMQGEYMVDCKKVPTLPTISFSLGGK 331

  Fly   402 KFVVKGNKMKLKVRTNRGRTVCISAVTEV----PDEPV-ILGDAFIRHFCTEFDLANNRIGFA 459
            .:.:.|.:..|| .:..|..:|:|....:    |..|: ||||.||..:.|.||..|||:|||
Zfish   332 VYSLTGEQYILK-ESQGGHDICLSGFMGLDIPPPAGPLWILGDVFIGQYYTVFDRENNRVGFA 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	125/327 (38%)
		Asp	149..460	CDD:278455	124/322 (39%)
ctsd	NP_571785.2	A1_Propeptide	19..44	CDD:285240	10/31 (32%)
		Cathepsin_D2	70..394	CDD:133157	125/327 (38%)
		Asp	75..395	CDD:278455	124/322 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.790