DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17283 and Pga5

DIOPT Version :9

Sequence 1:	NP_650621.1	Gene:	CG17283 / 42094	FlyBaseID:	FBgn0038505	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_068521.1	Gene:	Pga5 / 60372	RGDID:	621573	Length:	387	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	117/328 - (35%)
Similarity:	180/328 - (54%)	Gaps:	17/328 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 LKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSKACKKHKQYHPAKSSTYVKNGKS 206
            ::|..::.|...::||||.|:|.|:.|||||::|||..:|.|.||..||.::|.:|||::.:|:.
  Rat    66 MRNYLDLVYIGTISIGTPPQEFKVVLDTGSSDLWVPSIYCSSPACAHHKVFNPLQSSTFLVSGRP 130

  Fly   207 FAITYGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGLGYRSIAVDNVKT 271
            ..:.||||.::|.||.|||:|..|.|..|.|.::.:|||.....:.|||||||||.::.:..|..
  Rat   131 VNVAYGSGEMSGFLAYDTVKIGDLTVVAQAFGLSLEEPGRFMEHAVFDGILGLGYPNLGLQGVTP 195

  Fly   272 LVQNMCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQD 336
            :..|:..:.:|....||..:  .....:|..::.|..:.|.|.|  ...:.||:|..|||..:..
  Rat   196 VFDNLWIQGLIPQNLFAFYL--SSKDEKGSVLMLGGVDPSYYHG--ELHWVPVSKPSYWQLAVDS 256

  Fly   337 IYVGGTKVS--GSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKC--AKKIPDFTFV 397
            |.:.|..::  |..|.|:|:||||:|.|.:....|..:||.:|:..||.::||  ...:||..|.
  Rat   257 ISMNGEIIACDGGCQGIMDTGTSLVTGPRSSILNIQNLIGAKASGDGEYFLKCDTINTLPDIVFT 321

  Fly   398 IAGKKFVVKGNKMKLKVRTNRGRTVCISAVTEVPDEPV-----ILGDAFIRHFCTEFDLANNRIG 457
            |....:.|..:....|..::.    |.|...|..|:|.     :|||.|:|.:.|.||.||||||
  Rat   322 IDSVTYPVPASAYIRKDHSHN----CRSNFEESTDDPSDPELWVLGDVFLRLYFTVFDRANNRIG 382

  Fly   458 FAA 460
            .|:
  Rat   383 LAS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	116/325 (36%)
CG17283	NP_650621.1	Asp	149..460	CDD:278455	115/319 (36%)
Pga5	NP_068521.1	A1_Propeptide	16..44	CDD:285240
		pepsin_retropepsin_like	64..385	CDD:299705	116/326 (36%)
		Asp	74..386	CDD:278455	116/320 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930