Protein Alignment CG17283 and REN

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_000528.1
• Gene: REN / 5972
• HGNCID: 9958
• Length: 406
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 118/385 - (30%)
• Similarity: 191/385 - (49%)
• Gaps: 33/385 - (8%)

  Fly   103 LPLD---FQQNFVRTTDNLR---SEKAFLANRYGFSFAKSSGTATLKNTA---------NMEYTC 152
            ||.|   |::.|::...::|   .|:.....|.|..:::.....||.||.         :.:|..
Human    24 LPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYG 88

  Fly   153 KMNIGTPKQKFTVLPDTGSSNIWVPGPHCKS--KACKKHKQYHPAKSSTYVKNGKSFAITYGSGS 215
            ::.||||.|.|.|:.||||||:|||...|..  .||..||.:..:.||:|..||....:.|.:|:
Human    89 EIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGT 153

  Fly   216 VAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGLGYRSIAVDNVKTLVQNMCSED 280
            |:|.|::|.:.:.|:.|| |.|...|:.|...|:.:.|||::|:|:...|:..|..:..|:.|:.
Human   154 VSGFLSQDIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQG 217

  Fly   281 VITSCKFAICMK--GGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQDIYVGGTK 343
            |:....|:....  ...|.|.||.|:.|.|:...|.|  ::.|..:.|.|.||..::.:.||.:.
Human   218 VLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG--NFHYINLIKTGVWQIQMKGVSVGSST 280

  Fly   344 V--SGSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKC--AKKIPDFTFVIAGKKFV 404
            :  .....|:||:|.|.|:..|:...|:.:.:|.:.... :..:||  ...:||.:|.:.||::.
Human   281 LLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYT 344

  Fly   405 VKGNKMKLKVRTNRGRTVCISAVTEV----PDEPV-ILGDAFIRHFCTEFDLANNRIGFA 459
            :.......: .:...:.:|..|:..:    |..|. .||..|||.|.||||..|||||||
Human   345 LTSADYVFQ-ESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFA 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	106/338 (31%)
		Asp	149..460	CDD:278455	105/324 (32%)
REN	NP_000528.1	A1_Propeptide	33..>51	CDD:311771	3/17 (18%)
		renin_like	78..405	CDD:133154	105/331 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.790