Protein Alignment CG17283 and Bace2

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_062390.3
• Gene: Bace2 / 56175
• MGIID: 1860440
• Length: 514
• Species: Mus musculus
• Alignment Length: 444
• Identity: 110/444 - (24%)
• Similarity: 180/444 - (40%)
• Gaps: 111/444 - (25%)

  Fly    78 LARKSNRKIRA----KTESIVRSDS-SYATLPLDFQQNFVRTTDNLRSEKAFLANRYGFSFAKSS 137
            :||.:|.:..|    .|..:.|:|. :.|..|:....||:...|||:.:               |
Mouse    35 VARATNHRASAVPGLGTPELPRADGLALALEPVRATANFLAMVDNLQGD---------------S 84

  Fly   138 GTATLKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPG-PHCKSKACKKHKQYHPAKSSTYV 201
            |..         |..:|.||||.||..:|.||||||..|.| ||.....     .:....||||.
Mouse    85 GRG---------YYLEMLIGTPPQKVQILVDTGSSNFAVAGAPHSYIDT-----YFDSESSSTYH 135

  Fly   202 KNGKSFAITYGSGSVAGVLAKDTVRI-AGLVVTNQTFAMTTKEPGTTFVTSNF-------DGILG 258
            ..|....:.|..||..|.:.:|.|.| .|.   |.:|.:..   .|.|.:.||       :||||
Mouse   136 SKGFDVTVKYTQGSWTGFVGEDLVTIPKGF---NSSFLVNI---ATIFESENFFLPGIKWNGILG 194

  Fly   259 LGYRSIA--VDNVKTLVQNMCSEDVITSCKFAICMKG-----GGSSSRGGAIIFGSSNTSAYSGS 316
            |.|.::|  ..:::|...::.::..|... |::.|.|     .||.:.||:::.|....|.|.|
Mouse   195 LAYAALAKPSSSLETFFDSLVAQAKIPDI-FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKG- 257

  Fly   317 NSYTYTPVTKKGYWQFTLQDIYVGGTKVS------GSVQAIVDSGTSLITAPTAIYNKINKVIGC 375
             ...|||:.::.|:|..:..:.:||..::      .:.:|||||||:|:..|..:::.:.:.:..
Mouse   258 -DIWYTPIKEEWYYQIEILKLEIGGQNLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVAR 321

  Fly   376 RAT----SSG-------ECWMKCAKKIPDFTFVIAGKKFVVKGNKMKLKVR-TNRGRTVCISAVT 428
            .:.    |.|       .||.........|.             |:.:.:| .|..|:..|:.:.
Mouse   322 TSLIPEFSDGFWTGAQLACWTNSETPWAYFP-------------KISIYLRDENASRSFRITILP 373

  Fly   429 EVPDEP---------------------VILGDAFIRHFCTEFDLANNRIGFAAT 461
            ::..:|                     :::|...:..|...||.|..|:|||.:
Mouse   374 QLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQRRVGFAVS 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	92/371 (25%)
		Asp	149..460	CDD:278455	93/365 (25%)
Bace2	NP_062390.3	beta_secretase_like	85..446	CDD:133140	95/379 (25%)
		Asp	88..425	CDD:278455	92/363 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810