Protein Alignment CG17283 and PGA5

DIOPT Version :10

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_055039.1
• Gene: PGA5 / 5222
• HGNCID: 8887
• Length: 388
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 128/327 - (39%)
• Similarity: 186/327 - (56%)
• Gaps: 18/327 - (5%)

  Fly   142 LKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSKACKKHKQYHPAKSSTYVKNGKS 206
            |:|..:|||...:.||||.|.|||:.||||||:|||..:|.|.||..|.:::|..||||....::
Human    68 LENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSET 132

  Fly   207 FAITYGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGLGYRSIAVDNVKT 271
            .:||||:||:.|:|..|||::.|:..|||.|.::..|||:....:.|||||||.|.||:......
Human   133 VSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATP 197

  Fly   272 LVQNMCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQD 336
            :..|:.::.:::...|::.:.....|  |..:|||..::|.|:|  |..:.|||.:||||.|:..
Human   198 VFDNIWNQGLVSQDLFSVYLSADDKS--GSVVIFGGIDSSYYTG--SLNWVPVTVEGYWQITVDS 258

  Fly   337 IYVGGTKV--SGSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKCA--KKIPDFTFV 397
            |.:.|..:  :...|||||:||||:|.||:....|...||....|.|:..:.|:  ..:||..|.
Human   259 ITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFT 323

  Fly   398 IAGKKFVVKGNKMKLKVRTNRGRTVCISAV--TEVPDEP---VILGDAFIRHFCTEFDLANNRIG 457
            |.|.::.|..:...|:...:     |||..  ..||.|.   .||||.|||.:.|.||.|||::|
Human   324 INGVQYPVPPSAYILQSEGS-----CISGFQGMNVPTESGELWILGDVFIRQYFTVFDRANNQVG 383

  Fly   458 FA 459
            .|
Human   384 LA 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	Asp	149..460	CDD:394983	125/320 (39%)
PGA5	NP_055039.1	A1_Propeptide	19..45	CDD:462326
		pepsin_A	66..386	CDD:133145	128/327 (39%)