Protein Alignment CG17283 and Bace

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 157/365 - (43%)
• Similarity: 219/365 - (60%)
• Gaps: 25/365 - (6%)

  Fly   103 LPLDFQQNFVRTTDNLRSEKAFLANRYGFSFAKSSGTATLKNTANMEYTCKMNIGTPKQKFTVLP 167
            :|:..:||||:|..|:.:||::|..:|.....:|.....|.|:.||.|...::||||.|.|.||.
  Fly    22 VPILKEQNFVKTRQNVLAEKSYLRTKYQLPSLRSVDEEQLSNSMNMAYYGAISIGTPAQSFKVLF 86

  Fly   168 DTGSSNIWVPGPHCKSKACKKHKQYHPAKSSTYVKNGKSFAITYGSGSVAGVLAKDTVRIAGLVV 232
            |:||||:|||...|||.||..|.||..:.|||||.||:||:|.||:||:.|.|:.|||.:.||.:
  Fly    87 DSGSSNLWVPSNTCKSDACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVNGLSI 151

  Fly   233 TNQTFAMTTKEPGTTFVTSNFDGILGLGYRSIAVDNVKTLVQNMCSEDVITSCKFAICMKGGGSS 297
            .:||||.:|.||||.|..:|||||||:.|.|:|||.|.....||.|:.::.:..|:..:...|:|
  Fly   152 QSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTS 216

  Fly   298 SRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQDIYVGGTKVSGSVQAIVDSGTSLITAP 362
            :.||.:|||.|:.|.|||  :.||.|::::||||||:....:.|..:....|||.|:|||||.||
  Fly   217 TMGGELIFGGSDASLYSG--ALTYVPISEQGYWQFTMAGSSIDGYSLCDDCQAIADTGTSLIVAP 279

  Fly   363 TAIYNKINKVIG--------CRATSSGECWMKCAKKIPDFTFVIAGKKFVVKGNKMKLKVRTNRG 419
            ...|..:::::.        |.:.||          :||.||.|.|..||:|.:...::...|
  Fly   280 YNAYITLSEILNVGEDGYLDCSSVSS----------LPDVTFNIGGTNFVLKPSAYIIQSDGN-- 332

  Fly   420 RTVCISAVTEVPDEPVILGDAFIRHFCTEFDLANNRIGFA 459
               |:||...:..:..||||.||..:.|||||.|||||||
  Fly   333 ---CMSAFEYMGTDFWILGDVFIGQYYTEFDLGNNRIGFA 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	143/324 (44%)
		Asp	149..460	CDD:278455	141/319 (44%)
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	143/326 (44%)
		Asp	68..371	CDD:278455	141/319 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455534
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800