DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17283 and CG33128

DIOPT Version :9

Sequence 1:	NP_650621.1	Gene:	CG17283 / 42094	FlyBaseID:	FBgn0038505	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_787961.1	Gene:	CG33128 / 326263	FlyBaseID:	FBgn0053128	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	153/462 - (33%)
Similarity:	234/462 - (50%)	Gaps:	72/462 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVLCAFICLLVILTEARQRKVNHSADRRSLAVRSGHRNERSSALHGRGLAARSRNQRKRRLNAAK 70
            |||...:.|  :..|..:.|::.:.|         |:|              :|..||:.:.|.|
  Fly     5 LVLLTILAL--VSAEIHRIKIHKNQD---------HKN--------------TRQHRKQAIQALK 44

  Fly    71 RSRRKRNLARKSNRKIRAKTESIVRSDSSYATLPLDFQQNFVRTTDNLRSEKAFLANRYGFSFAK 135
            ....::::.             |:..|.    :|:..|.:                  ||:.:..
  Fly    45 LKYHQQDVV-------------IIYDDG----VPIYMQPD------------------YGYDYPS 74

  Fly   136 SSG----TATLKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSK--ACKKHKQYHP 194
            .:.    :..|.|:.||.|...:.||||:|.|.|:.||||:|:|||...|.:.  ||::|.||:.
  Fly    75 QTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQHNQYNS 139

  Fly   195 AKSSTYVKNGKSFAITYGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGL 259
            :.|||:|.:|::|:|.||:|||:|.||.|||.|.||.:.||||.....:||.:|....||||||:
  Fly   140 SASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAVSQPGASFTDVAFDGILGM 204

  Fly   260 GYRSIAVDNVKTLVQNMCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPV 324
            ||:.||.|||.....|:..|.:|....|...:...||:..||.:..|.::.:..:|  ..|||||
  Fly   205 GYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTLGGTDQNLIAG--EMTYTPV 267

  Fly   325 TKKGYWQFTLQDIYVGGTKVSGSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKCA- 388
            |::|||||.:.:|...||.:|...|||.|:|||||.||:|.|.::|.:|| .....|:.::.|:
  Fly   268 TQQGYWQFAVNNITWNGTVISSGCQAIADTGTSLIAAPSAAYIQLNNLIG-GVPIQGDYYVPCST 331

  Fly   389 -KKIPDFTFVIAGKKFVVKGNKMKLKVRTNRGRTVCISAVTEVPDEPVILGDAFIRHFCTEFDLA 452
             ..:|..|..|.|..|.:..: :.::..|....|.|:|..|::.....||||.|:..:.:|||..
  Fly   332 VSSLPVLTINIGGTNFYLPPS-VYIQTYTEGNYTTCMSTFTDIGTGFWILGDVFLGQYYSEFDFG 395

  Fly   453 NNRIGFA 459
            .||:|||
  Fly   396 QNRVGFA 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	131/320 (41%)
CG17283	NP_650621.1	Asp	149..460	CDD:278455	129/315 (41%)
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:299705	133/324 (41%)
CG33128	NP_787961.1	Asp	92..404	CDD:278455	129/315 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455550
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800