Protein Alignment CG17283 and Bace2

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001002802.1
• Gene: Bace2 / 288227
• RGDID: 1303241
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 112/479 - (23%)
• Similarity: 181/479 - (37%)
• Gaps: 143/479 - (29%)

  Fly    39 SGHRNERSSALHGRGLAARSRNQRKRRLNAAKRSRRKRNLARKSNRKIRAKTESIVRSDS-SYAT 102
            :|..|.|:|.:.|.|                                    |..:.|:|. :.|.
  Rat    36 AGAANHRASTVPGLG------------------------------------TPELPRADGLALAL 64

  Fly   103 LPLDFQQNFVRTTDNLRSEKAFLANRYGFSFAKSSGTATLKNTANMEYTCKMNIGTPKQKFTVLP 167
            .|.....||:...|||:.:               ||..         |..:|.||||.||..:|.
  Rat    65 EPARATANFLAMVDNLQGD---------------SGRG---------YYLEMLIGTPPQKVRILV 105

  Fly   168 DTGSSNIWVPG-PHCKSKACKKHKQYHPAKSSTYVKNGKSFAITYGSGSVAGVLAKDTVRI-AGL 230
            ||||||..|.| ||.....     .:....||||...|....:.|..||..|.:.:|.|.| .|.
  Rat   106 DTGSSNFAVAGAPHSYIDT-----YFDSESSSTYHSKGFEVTVKYTQGSWTGFVGEDLVTIPKGF 165

  Fly   231 VVTNQTFAMTTKEPGTTFVTSNF-------DGILGLGYRSIA--VDNVKTLVQNMCSEDVITSCK 286
               |.:|.:..   .|.|.:.||       :|||||.|.::|  ..:::|...::.::..|...
  Rat   166 ---NSSFLVNI---ATIFESENFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDI- 223

  Fly   287 FAICMKG-----GGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTKKGYWQFTLQDIYVGGTKVS- 345
            |::.|.|     .||.:.||:::.|....|.|.|  ...|||:.::.|:|..:..:.:||..::
  Rat   224 FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKG--DIWYTPIKEEWYYQIEILKLEIGGQSLNL 286

  Fly   346 -----GSVQAIVDSGTSLITAPTAIYNKINKVIGCRAT----SSG-------ECWMKCAKKIPDF 394
                 .:.:|||||||:|:..|..:::.:.:.:...:.    |.|       .||.........|
  Rat   287 DCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYF 351

  Fly   395 TFVIAGKKFVVKGNKMKLKVR-TNRGRTVCISAVTEVPDEP---------------------VIL 437
            .             |:.:.:| .|..|:..|:.:.::..:|                     :::
  Rat   352 P-------------KISIYLRDENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVI 403

  Fly   438 GDAFIRHFCTEFDLANNRIGFAAT 461
            |...:..|...||.|..|:|||.:
  Rat   404 GATVMEGFYVVFDRAQRRVGFAVS 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	92/371 (25%)
		Asp	149..460	CDD:278455	93/365 (25%)
Bace2	NP_001002802.1	beta_secretase_like	85..446	CDD:133140	95/379 (25%)
		Asp	88..425	CDD:278455	92/363 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810