Protein Alignment CG17283 and CTSE

DIOPT Version :9

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_011507546.1
• Gene: CTSE / 1510
• HGNCID: 2530
• Length: 401
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 140/337 - (41%)
• Similarity: 193/337 - (57%)
• Gaps: 18/337 - (5%)

  Fly   137 SGTATLKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPGPHCKSKACKKHKQYHPAKSSTYV 201
            |....|.|..:|||...::||:|.|.|||:.||||||:|||..:|.|.|||.|.::.|::||||.
Human    65 SAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSPACKTHSRFQPSQSSTYS 129

  Fly   202 KNGKSFAITYGSGSVAGVLAKDTV-----RIAGLVVTNQTFAMTTKEPGTTFVTSNFDGILGLGY 261
            :.|:||:|.||:||::|::..|.|     ::.||.|..|.|..:..|||.|||.:.|||||||||
Human   130 QPGQSFSIQYGTGSLSGIIGADQVSAFSYQVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGY 194

  Fly   262 RSIAVDNVKTLVQNMCSEDVITSCKFAICMKGGGSSSRGGAIIFGSSNTSAYSGSNSYTYTPVTK 326
            .|:||..|..:..||.:::::....|::.|........|..:|||..:.|.:||  |..:.||||
Human   195 PSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG--SLNWVPVTK 257

  Fly   327 KGYWQFTLQDIYVGGTKV--SGSVQAIVDSGTSLITAPTAIYNKINKVIGCRATSSGECWMKCA- 388
            :.|||..|.:|.||||.:  |...|||||:||||||.|:....::...||. |...||..::||
Human   258 QAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA-APVDGEYAVECAN 321

  Fly   389 -KKIPDFTFVIAGKKFVVKGNKMKLKVRTNRGRTVCISAVTEV----PDEPV-ILGDAFIRHFCT 447
             ..:||.||.|.|..:.:......|....: |...|.|....:    |..|: ||||.|||.|.:
Human   322 LNVMPDVTFTINGVPYTLSPTAYTLLDFVD-GMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYS 385

  Fly   448 EFDLANNRIGFA 459
            .||..|||:|.|
Human   386 VFDRGNNRVGLA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	pepsin_retropepsin_like	142..459	CDD:299705	138/330 (42%)
		Asp	149..460	CDD:278455	136/325 (42%)
CTSE	XP_011507546.1	A1_Propeptide	21..49	CDD:285240
		Asp	77..399	CDD:278455	136/325 (42%)
		Cathespin_E	78..398	CDD:133153	135/324 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.760