Protein Alignment CG17283 and bace2

DIOPT Version :10

• Sequence 1: NP_650621.1
• Gene: CG17283 / 42094
• FlyBaseID: FBgn0038505
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001135590.1
• Gene: bace2 / 100216145
• XenbaseID: XB-GENE-1014090
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 373
• Identity: 100/373 - (26%)
• Similarity: 159/373 - (42%)
• Gaps: 76/373 - (20%)

  Fly   142 LKNTANMEYTCKMNIGTPKQKFTVLPDTGSSNIWVPG---PHCKSKACKKHKQYHPAKSST-YVK 202
            |:..:...|..::.||||.||..:|.||||||..|.|   |...:        :..:|.|| |..
 Frog    67 LEGDSGRGYYLELLIGTPPQKMNILVDTGSSNFAVAGALNPDITT--------FFDSKLSTSYEP 123

  Fly   203 NGKSFAITYGSGSVAGVLAKDTVRIAGLVVTNQTFAMTTKEPGTTFVTSNF-------DGILGLG 260
            ......:.|..||..|:|.||.:.:...|  |.||.:..   .:.|.:.||       .|||||.
 Frog   124 LNTQVTVRYTQGSWTGLLGKDVISMPKGV--NGTFLINI---ASIFQSENFFLPNINWQGILGLA 183

  Fly   261 YRSIA--VDNVKTLVQNMCSEDVITSCKFAICMKGGGSSSRG-----GAIIFGSSNTSAYSGSNS 318
            |.::|  ..:|:....::..::.|.:. |::.|.|.|..|.|     |:::.|....|.|.|  .
 Frog   184 YSTLAKPSSSVEPFFDSLVQQENIPNI-FSMQMCGAGQPSPGIGINAGSLVLGGIEPSLYQG--D 245

  Fly   319 YTYTPVTKKGYWQFTLQDIYVGGTK------VSGSVQAIVDSGTSLITAPTAIYN-KINKVIGCR 376
            ..|||:|::.|:|..:....|||..      |..|.:|||||||:|:..|..::| .::.::
 Frog   246 IWYTPITEEWYYQVEVLKFEVGGQNLNLDCTVYNSDKAIVDSGTTLLRLPDKVFNAMVDAIV--- 307

  Fly   377 ATS-----SGECW----MKCAKK-------IPDFTFVI----AGKKFVVKGNKMKLK-------V 414
            .||     :.|.|    :.|..|       .||.:..:    :.:.|     ::.||       |
 Frog   308 QTSLIQNFNAEFWAGLQLACWDKTQDPWNYFPDISIYLRDTNSSRSF-----RLTLKPQLYIQSV 367

  Fly   415 RTNRGRTVCISAVTEVPDEPVILGDAFIRHFCTEFDLANNRIGFAATT 462
            .|.:....|...........:::|...:..|...||.|..|:|||.::
 Frog   368 LTFQESLNCFRFGISQSASALVIGATVMEGFYVIFDRAEKRVGFAVSS 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17283	NP_650621.1	Asp	149..460	CDD:394983	98/362 (27%)
bace2	NP_001135590.1	beta_secretase_like	72..433	CDD:133140	99/368 (27%)