DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sur-8 and AT1G61180

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_001031216.1	Gene:	AT1G61180 / 842411	AraportID:	AT1G61180	Length:	899	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	134/598 - (22%)
Similarity:	239/598 - (39%)	Gaps:	144/598 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 RPKMVTVKHPE------SNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPST 178
            :|..|....||      .||....|..|.|:..:. ..:..|:||  |:. |.|:....|:...|
plant   302 KPMQVNCLEPEDAWELFKNKVGDNTLSSDPVIVEL-AREVAQKCR--GLP-LALNVIGETMSSKT 362

  Fly   179 -VKECVHLTELYLYS--------NKIGQLPPEIGCLVSLRNLALNENSLTSL-PESLQNCSQLKV 233
             |:|..|...::..|        |||               |.:.:.|..|| .|.:::|.....
plant   363 MVQEWEHAIHVFNTSAAEFSDMQNKI---------------LPILKYSYDSLGDEHIKSCFLYCA 412

  Fly   234 L-----DLRHNKLAEI---------PPVIYRLRS-----LTTLYLRFNRITAVA-------DDLR 272
            |     ::.:.||.:.         ..||.|.|:     |.|| .|.|.:|.|.       |.:|
plant   413 LFPEDGEIYNEKLIDYWICEGFIGEDQVIKRARNKGYAMLGTL-TRANLLTKVGTYYCVMHDVVR 476

  Fly   273 QLVNLTMLS----LRENKIRELGSAI---------GALVNLTTLDVSHNHLEHLPEDIGNCVNLS 324
            ::. |.:.|    .:||.:.:.|..:         ||:..::.:|   |.:|.:..: ..|..|:
plant   477 EMA-LWIASDFGKQKENFVVQAGVGLHEIPKVKDWGAVRKMSLMD---NDIEEITCE-SKCSELT 536

  Fly   325 ALDLQHNELLDIPDS-IGNLKSLVRLGMRYNR-LSSVPATLKNCKSMDEFNVEGNGITQLPDGML 387
            .|.||.|:|.::|.: |..::.||.|.:.||| .:.:|..:....|:...::....|..:|.| |
plant   537 TLFLQSNKLKNLPGAFIRYMQKLVVLDLSYNRDFNKLPEQISGLVSLQFLDLSNTSIEHMPIG-L 600

  Fly   388 ASLSGLTTITLS-RNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKL-NMKENM 450
            ..|..||.:.|: .::..|  ..|.::..::..:.|..:::    :|..|..|.|.:| |::|..
plant   601 KELKKLTFLDLTYTDRLCS--ISGISRLLSLRLLRLLGSKV----HGDASVLKELQQLQNLQELA 659

  Fly   451 LTALPLDIGTWVNMVEL--NLATNALQKLPDD---IMNLQNLEILILSNNMLKKIPNTIGNLRKL 510
            :|.....|.....:.:|  ||......:.|.|   :.:::||..|.:.|:...:|        |.
plant   660 ITVSAELISLDQRLAKLISNLCIEGFLQKPFDLSFLASMENLSSLRVENSYFSEI--------KC 716

  Fly   511 RILDLEENRIEVLPH----------EIGLLHELQRL---ILQTNQITML---PRSIGHL------ 553
            |..:.|.:.:.:.|.          ||...|.::.|   :...|.:.:|   .|.:|.:
plant   717 RESETESSYLRINPKIPCFTNLSRLEIMKCHSMKDLTWILFAPNLVVLLIEDSREVGEIINKEKA 781

  Fly   554 GNLTHLSVSENNLQFLPEE---IGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLST 615
            .|||.::      .||..|   :.:|..||::|.:..|....|..:::.|..|:.|.::...:|.
plant   782 TNLTSIT------PFLKLEWLILYNLPKLESIYWSPLPFPVLLTMDVSNCPKLRKLPLNATSVSK 840

  Fly   616 I---------PPE 619
            :         |||
plant   841 VEEFEIHMYPPPE 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	6/21 (29%)
		leucine-rich repeat	185..207	CDD:275380	4/29 (14%)
		LRR_RI	204..401	CDD:238064	57/239 (24%)
		LRR_8	207..264	CDD:290566	18/76 (24%)
		leucine-rich repeat	208..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..253	CDD:275380	6/35 (17%)
		LRR_8	252..310	CDD:290566	19/82 (23%)
		leucine-rich repeat	254..276	CDD:275380	9/28 (32%)
		leucine-rich repeat	277..299	CDD:275380	7/34 (21%)
		LRR_8	299..356	CDD:290566	18/58 (31%)
		leucine-rich repeat	300..322	CDD:275380	4/21 (19%)
		leucine-rich repeat	323..345	CDD:275380	8/22 (36%)
		LRR_8	344..403	CDD:290566	16/60 (27%)
		leucine-rich repeat	346..368	CDD:275380	7/22 (32%)
		leucine-rich repeat	369..392	CDD:275380	5/22 (23%)
		LRR_RI	<379..566	CDD:238064	45/215 (21%)
		leucine-rich repeat	417..440	CDD:275380	3/22 (14%)
		leucine-rich repeat	441..486	CDD:275380	11/50 (22%)
		LRR_8	463..520	CDD:290566	13/61 (21%)
		leucine-rich repeat	487..507	CDD:275380	4/19 (21%)
		leucine-rich repeat	510..532	CDD:275380	5/31 (16%)
		LRR_8	532..588	CDD:290566	15/70 (21%)
		leucine-rich repeat	556..578	CDD:275380	6/24 (25%)
		leucine-rich repeat	603..626	CDD:275380	6/26 (23%)
AT1G61180	NP_001031216.1	NB-ARC	156..440	CDD:279299	33/156 (21%)
		leucine-rich repeat	513..534	CDD:275378	4/24 (17%)
		LRR_8	533..593	CDD:290566	16/59 (27%)
		leucine-rich repeat	535..558	CDD:275378	8/22 (36%)
		leucine-rich repeat	559..582	CDD:275378	7/22 (32%)
		leucine-rich repeat	583..605	CDD:275378	5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287114at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010