DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sur-8 and AT5G23400

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_197731.1	Gene:	AT5G23400 / 832405	AraportID:	AT5G23400	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	449	Identity:	126/449 - (28%)
Similarity:	207/449 - (46%)	Gaps:	77/449 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 IPSTVKECVHLTELYLYSNKI-------------------------GQLPPEIGCLVSLRNLALN 214
            ||::......|.:|.|..|.:                         |.:|...|.|..|..:.|.
plant   124 IPNSFSNLTSLRQLILDDNSLQGNVLSSLGHLPLLEILSLAGNRFSGLVPASFGSLRRLTTMNLA 188

  Fly   215 ENSLTS-LPESLQNCSQLKVLDLRHNKLA-EIPPVIYRLRSLTTLYLRFNRITAVAD-DLRQLVN 276
            .||.:. :|.:.:|..:|:.|||..|.|: .||..|.:.::||.|||..||.:.|.. .:..|..
plant   189 RNSFSGPIPVTFKNLLKLENLDLSSNLLSGPIPDFIGQFQNLTNLYLSSNRFSGVLPVSVYSLRK 253

  Fly   277 LTMLSLRENKIR-ELGSAIGALVNLTTLDVSHN-HLEHLPEDIGNCVNLSALDLQHNELLDIPDS 339
            |..:||..|.:. .|......|.:||:|.:|.| .:.|:|..|....||.:|:|..|...|....
plant   254 LQTMSLERNGLTGPLSDRFSYLKSLTSLQLSGNKFIGHIPASITGLQNLWSLNLSRNLFSDPLPV 318

  Fly   340 IG--NLKSLVRLGMRYNRLS--SVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTIT--- 397
            :|  ...||:.:.:.||.|:  ::|:.::: |.:.:.|:.|..:.    |....|:..||:|
plant   319 VGARGFPSLLSIDLSYNNLNLGAIPSWIRD-KQLSDINLAGCKLR----GTFPKLTRPTTLTSLD 378

  Fly   398 LSRNQFASYPTGGPAQF----TNVYSINLEHN--RID----KIPYGIFSRAKGLTKLNMKENMLT 452
            ||.|    :.||..:.|    |||..:.|..|  |.|    |:|.|:.|       :::..|::|
plant   379 LSDN----FLTGDVSAFLTSLTNVQKVKLSKNQLRFDLSKLKLPEGVAS-------IDLSSNLVT 432

  Fly   453 ALPLDIGTWVN------MVELNLATNALQ-KLPDDIMNLQNLEIL-ILSNNMLKKIPNTIGNLRK 509
            .   .:.:.:|      :.|::|..|.:. ::||...:| ||::| |.||.:..:||::|.||.:
plant   433 G---SLSSLINNKTSSFLEEIHLTNNQISGRIPDFGESL-NLKVLNIGSNKISGQIPSSISNLVE 493

  Fly   510 LRILDLEENRIE-VLPHEIGLLHELQRLILQTNQIT-MLPRSIGHLGNLTHLSVSENNL 566
            |..||:..|.|. .:|..||.|.:|:.|.|..|.:| .:|.|:.::..:.|.|...|.|
plant   494 LVRLDISRNHITGGIPQAIGQLAQLKWLDLSINALTGRIPDSLLNIKTIKHASFRANRL 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	2/8 (25%)
		leucine-rich repeat	185..207	CDD:275380	8/46 (17%)
		LRR_RI	204..401	CDD:238064	62/208 (30%)
		LRR_8	207..264	CDD:290566	21/58 (36%)
		leucine-rich repeat	208..230	CDD:275380	6/22 (27%)
		leucine-rich repeat	231..253	CDD:275380	9/22 (41%)
		LRR_8	252..310	CDD:290566	20/60 (33%)
		leucine-rich repeat	254..276	CDD:275380	9/22 (41%)
		leucine-rich repeat	277..299	CDD:275380	6/22 (27%)
		LRR_8	299..356	CDD:290566	19/59 (32%)
		leucine-rich repeat	300..322	CDD:275380	8/22 (36%)
		leucine-rich repeat	323..345	CDD:275380	6/23 (26%)
		LRR_8	344..403	CDD:290566	17/63 (27%)
		leucine-rich repeat	346..368	CDD:275380	5/23 (22%)
		leucine-rich repeat	369..392	CDD:275380	4/22 (18%)
		LRR_RI	<379..566	CDD:238064	61/209 (29%)
		leucine-rich repeat	417..440	CDD:275380	9/28 (32%)
		leucine-rich repeat	441..486	CDD:275380	9/51 (18%)
		LRR_8	463..520	CDD:290566	22/64 (34%)
		leucine-rich repeat	487..507	CDD:275380	8/20 (40%)
		leucine-rich repeat	510..532	CDD:275380	9/22 (41%)
		LRR_8	532..588	CDD:290566	11/36 (31%)
		leucine-rich repeat	556..578	CDD:275380	4/11 (36%)
		leucine-rich repeat	603..626	CDD:275380
AT5G23400	NP_197731.1	PLN00113	39..>557	CDD:215061	126/449 (28%)
		leucine-rich repeat	109..133	CDD:275380	2/8 (25%)
		leucine-rich repeat	134..157	CDD:275380	4/22 (18%)
		leucine-rich repeat	158..181	CDD:275380	4/22 (18%)
		leucine-rich repeat	182..205	CDD:275380	6/22 (27%)
		leucine-rich repeat	206..229	CDD:275380	9/22 (41%)
		leucine-rich repeat	230..253	CDD:275380	9/22 (41%)
		leucine-rich repeat	254..277	CDD:275380	6/22 (27%)
		leucine-rich repeat	278..301	CDD:275380	8/22 (36%)
		leucine-rich repeat	302..326	CDD:275380	6/23 (26%)
		leucine-rich repeat	374..397	CDD:275380	7/26 (27%)
		leucine-rich repeat	398..440	CDD:275380	11/51 (22%)
		leucine-rich repeat	447..469	CDD:275380	6/22 (27%)
		leucine-rich repeat	470..493	CDD:275380	10/22 (45%)
		leucine-rich repeat	494..517	CDD:275380	9/22 (41%)
		leucine-rich repeat	518..536	CDD:275380	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54393
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010