DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sur-8 and PIRL8

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_194335.2	Gene:	PIRL8 / 828711	AraportID:	AT4G26050	Length:	383	Species:	Arabidopsis thaliana

Alignment Length:	325	Identity:	96/325 - (29%)
Similarity:	150/325 - (46%)	Gaps:	75/325 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 TAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPED-IGNCVNLSALDL 328
            ||...|.||  |:..|.|....:..|.::...|.:::.||:|:|:::.:||. :...:||.||||
plant    49 TAKEGDRRQ--NIKTLDLSGMSLASLSASSINLASISKLDLSNNNIQKIPESLVARMLNLWALDL 111

  Fly   329 QHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGL 393
            |.|:|..:|:|||.|..|..|.:..|.|.|:|.|:::|:|::|.|...|.:|:|||.:     |.
plant   112 QSNQLKTLPNSIGCLSKLKFLNVSGNYLQSLPKTIEDCRSLEELNANFNELTRLPDAI-----GF 171

  Fly   394 TTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDI 458
                               :.||                        ||||::..|.|..||..:
plant   172 -------------------ELTN------------------------LTKLSVNSNKLVLLPNSV 193

  Fly   459 GTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVL 523
            ....::..|:...|.|..||:|:.||.||::|.:|.|.                     ..:..|
plant   194 SYLTSLRVLDARLNRLSSLPEDLENLVNLQVLNVSQNF---------------------QHLTTL 237

  Fly   524 PHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEI--GSLESLENLYINQ 586
            |:.:|||..|..|.:..|.||:||.|:|.|..:..|||..|.|...|.|:  ..||:|:. |:::
plant   238 PYSVGLLISLVELDVSYNGITVLPDSLGCLRRIQKLSVEGNPLISPPFEVVEQGLEALKQ-YMSE 301

Fly 587 586
plant 302 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380
		leucine-rich repeat	185..207	CDD:275380
		LRR_RI	204..401	CDD:238064	47/136 (35%)
		LRR_8	207..264	CDD:290566
		leucine-rich repeat	208..230	CDD:275380
		leucine-rich repeat	231..253	CDD:275380
		LRR_8	252..310	CDD:290566	14/44 (32%)
		leucine-rich repeat	254..276	CDD:275380	5/10 (50%)
		leucine-rich repeat	277..299	CDD:275380	4/21 (19%)
		LRR_8	299..356	CDD:290566	23/57 (40%)
		leucine-rich repeat	300..322	CDD:275380	6/22 (27%)
		leucine-rich repeat	323..345	CDD:275380	13/21 (62%)
		LRR_8	344..403	CDD:290566	17/58 (29%)
		leucine-rich repeat	346..368	CDD:275380	8/21 (38%)
		leucine-rich repeat	369..392	CDD:275380	7/22 (32%)
		LRR_RI	<379..566	CDD:238064	47/186 (25%)
		leucine-rich repeat	417..440	CDD:275380	0/22 (0%)
		leucine-rich repeat	441..486	CDD:275380	16/44 (36%)
		LRR_8	463..520	CDD:290566	13/56 (23%)
		leucine-rich repeat	487..507	CDD:275380	4/19 (21%)
		leucine-rich repeat	510..532	CDD:275380	5/21 (24%)
		LRR_8	532..588	CDD:290566	21/57 (37%)
		leucine-rich repeat	556..578	CDD:275380	8/23 (35%)
		leucine-rich repeat	603..626	CDD:275380
PIRL8	NP_194335.2	PRK15370	<81..>308	CDD:185268	86/291 (30%)
		leucine-rich repeat	84..105	CDD:275380	6/20 (30%)
		leucine-rich repeat	106..128	CDD:275380	13/21 (62%)
		leucine-rich repeat	129..151	CDD:275380	8/21 (38%)
		leucine-rich repeat	152..175	CDD:275380	8/46 (17%)
		leucine-rich repeat	176..198	CDD:275380	8/21 (38%)
		leucine-rich repeat	199..221	CDD:275380	8/21 (38%)
		leucine-rich repeat	222..246	CDD:275380	9/44 (20%)
		leucine-rich repeat	247..269	CDD:275380	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3538
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910