DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sur-8 and BAM3

DIOPT Version :9

Sequence 1:NP_001262665.1 Gene:Sur-8 / 42093 FlyBaseID:FBgn0038504 Length:694 Species:Drosophila melanogaster
Sequence 2:NP_193760.1 Gene:BAM3 / 827774 AraportID:AT4G20270 Length:992 Species:Arabidopsis thaliana


Alignment Length:653 Identity:174/653 - (26%)
Similarity:263/653 - (40%) Gaps:140/653 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   159 DEGIKRLDLSKSSI--TVIPSTVKECVHLTELYLYSNKI-GQLPPEIGCLVSLR--NLALN---- 214
            ::.|.|||||..:|  |:.|...:....|..|.:.||.. |:||.||..|..|.  |::.|    
plant    75 NQSITRLDLSNLNISGTISPEISRLSPSLVFLDISSNSFSGELPKEIYELSGLEVLNISSNVFEG 139

  Fly   215 -------------------ENSLT-SLPESLQNCSQLKVLDLRHNKL-AEIPPVIYRLRSLTTLY 258
                               :||.. |||.||...::|:.|||..|.. .|||.......||..|.
plant   140 ELETRGFSQMTQLVTLDAYDNSFNGSLPLSLTTLTRLEHLDLGGNYFDGEIPRSYGSFLSLKFLS 204

  Fly   259 LRFNRITA-VADDLRQLVNLTMLSL-RENKIR-ELGSAIGALVNLTTLDVSHNHLE-HLPEDIGN 319
            |..|.:.. :.::|..:..|..|.| ..|..| .:.:..|.|:||..||:::..|: .:|.::||
plant   205 LSGNDLRGRIPNELANITTLVQLYLGYYNDYRGGIPADFGRLINLVHLDLANCSLKGSIPAELGN 269

  Fly   320 CVNLSALDLQHNELL-DIPDSIGNLKSLVRLGMRYNRL-SSVPATLKNCKSMDEFNVEGNG---- 378
            ..||..|.||.|||. .:|..:||:.||..|.:..|.| ..:|..|...:.:..||:..|.    
plant   270 LKNLEVLFLQTNELTGSVPRELGNMTSLKTLDLSNNFLEGEIPLELSGLQKLQLFNLFFNRLHGE 334

  Fly   379 ----ITQLPD----------------GMLASLSGLTTITLSRNQFASYPTG-------------- 409
                :::|||                ..|.|...|..|.||.|:.    ||              
plant   335 IPEFVSELPDLQILKLWHNNFTGKIPSKLGSNGNLIEIDLSTNKL----TGLIPESLCFGRRLKI 395

  Fly   410 ---------GP-----AQFTNVYSINLEHNRI-DKIPYGIFSRAKGLTKLNMKENMLTA-LPLD- 457
                     ||     .|...::...|..|.: .|:|.|:. ....|:.|.::.|.||. :|.: 
plant   396 LILFNNFLFGPLPEDLGQCEPLWRFRLGQNFLTSKLPKGLI-YLPNLSLLELQNNFLTGEIPEEE 459

  Fly   458 --IGTWVNMVELNLATNALQ-KLPDDIMNLQNLEILILSNNMLK-KIPNTIGNLRKLRILDLEEN 518
              ...:.::.::||:.|.|. .:|..|.||::|:||:|..|.|. :||..||:|:.|..:|:..|
plant   460 AGNAQFSSLTQINLSNNRLSGPIPGSIRNLRSLQILLLGANRLSGQIPGEIGSLKSLLKIDMSRN 524

  Fly   519 RIE-VLPHEIGLLHELQRLILQTNQIT-MLPRSIGHLGNLTHLSVSENNL-QFLPEEIGSLESLE 580
            ... ..|.|.|....|..|.|..|||: .:|..|..:..|.:|:||.|:. |.||.|:|.::||.
plant   525 NFSGKFPPEFGDCMSLTYLDLSHNQISGQIPVQISQIRILNYLNVSWNSFNQSLPNELGYMKSLT 589

  Fly   581 NLYINQNPGLEKLPF--ELALCQNLKYL-NIDKCPLSTIP---------------------PEIQ 621
            :...:.|.....:|.  :.:...|..:| |...|..|:.|                     .||.
plant   590 SADFSHNNFSGSVPTSGQFSYFNNTSFLGNPFLCGFSSNPCNGSQNQSQSQLLNQNNARSRGEIS 654

  Fly   622 AG----------GPSLVLQWLKMHSPYRQMXDVDGVWRTV---YVGSDCYYQYELQTVNQAPGAG 673
            |.          |..||...|.:....|...:...:|:.:   .:|....:..|....|...|.|
plant   655 AKFKLFFGLGLLGFFLVFVVLAVVKNRRMRKNNPNLWKLIGFQKLGFRSEHILECVKENHVIGKG 719

  Fly   674 GNG 676
            |.|
plant   720 GRG 722

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sur-8NP_001262665.1 leucine-rich repeat 163..184 CDD:275380 8/22 (36%)
leucine-rich repeat 185..207 CDD:275380 10/22 (45%)
LRR_RI 204..401 CDD:238064 70/253 (28%)
LRR_8 207..264 CDD:290566 23/83 (28%)
leucine-rich repeat 208..230 CDD:275380 10/47 (21%)
leucine-rich repeat 231..253 CDD:275380 8/22 (36%)
LRR_8 252..310 CDD:290566 17/60 (28%)
leucine-rich repeat 254..276 CDD:275380 5/22 (23%)
leucine-rich repeat 277..299 CDD:275380 7/23 (30%)
LRR_8 299..356 CDD:290566 23/58 (40%)
leucine-rich repeat 300..322 CDD:275380 7/22 (32%)
leucine-rich repeat 323..345 CDD:275380 10/22 (45%)
LRR_8 344..403 CDD:290566 20/83 (24%)
leucine-rich repeat 346..368 CDD:275380 6/22 (27%)
leucine-rich repeat 369..392 CDD:275380 8/46 (17%)
LRR_RI <379..566 CDD:238064 64/239 (27%)
leucine-rich repeat 417..440 CDD:275380 5/23 (22%)
leucine-rich repeat 441..486 CDD:275380 14/49 (29%)
LRR_8 463..520 CDD:290566 22/58 (38%)
leucine-rich repeat 487..507 CDD:275380 10/20 (50%)
leucine-rich repeat 510..532 CDD:275380 6/22 (27%)
LRR_8 532..588 CDD:290566 20/57 (35%)
leucine-rich repeat 556..578 CDD:275380 10/22 (45%)
leucine-rich repeat 603..626 CDD:275380 9/54 (17%)
BAM3NP_193760.1 LRRNT_2 34..72 CDD:285463
PLN00113 37..986 CDD:215061 174/653 (27%)
leucine-rich repeat 79..102 CDD:275380 8/22 (36%)
leucine-rich repeat 103..126 CDD:275380 10/22 (45%)
leucine-rich repeat 127..151 CDD:275380 3/23 (13%)
leucine-rich repeat 152..175 CDD:275380 7/22 (32%)
leucine-rich repeat 176..199 CDD:275380 8/22 (36%)
leucine-rich repeat 200..223 CDD:275380 5/22 (23%)
leucine-rich repeat 224..248 CDD:275380 7/23 (30%)
leucine-rich repeat 249..272 CDD:275380 7/22 (32%)
LRR_RI 270..574 CDD:238064 85/308 (28%)
leucine-rich repeat 273..296 CDD:275380 10/22 (45%)
leucine-rich repeat 297..318 CDD:275380 6/20 (30%)
leucine-rich repeat 321..344 CDD:275380 4/22 (18%)
leucine-rich repeat 345..368 CDD:275380 2/22 (9%)
leucine-rich repeat 369..392 CDD:275380 7/26 (27%)
leucine-rich repeat 393..414 CDD:275380 2/20 (10%)
leucine-rich repeat 441..467 CDD:275380 6/25 (24%)
leucine-rich repeat 468..491 CDD:275380 8/22 (36%)
leucine-rich repeat 492..513 CDD:275380 10/20 (50%)
leucine-rich repeat 564..587 CDD:275380 10/22 (45%)
PKc_like 716..984 CDD:304357 4/7 (57%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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