DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sur-8 and RLP36

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_188941.1	Gene:	RLP36 / 821875	AraportID:	AT3G23010	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	457	Identity:	121/457 - (26%)
Similarity:	191/457 - (41%)	Gaps:	72/457 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 SITVIPSTVK------------------ECVHLTELYL-YSNKIGQLPPEIGCLVSLRNLALNEN 216
            |:.:|||.|.                  ....|..||: ::|..|.:|..|..||:|..|.::.|
plant    86 SLLMIPSLVHIDLSQNHFEGPIDFRNTFSLSRLRVLYVGFNNLDGLIPESISKLVNLEYLDVSHN 150

  Fly   217 SL-TSLPESLQNCSQLKVLDLRHNKL-AEIPPVIYRLRSLTTLYLRFNRITAVADDLRQL--VNL 277
            :. ..:|.|:.....|..:||.:||| .::|..::|...|..:.|.:|.....|..:..:  .:|
plant   151 NFGGQVPRSISKVVNLTSVDLSYNKLEGQVPDFVWRSSKLDYVDLSYNSFNCFAKSVEVIDGASL 215

  Fly   278 TMLSLRENKI-RELGSAIGALVNLTTLDVSHNHLE-HLPEDIGNCVNLSALDLQHNEL------L 334
            |||:|..|.: ......|..:.:|..||:|:||.. .:|:.:........|:|::|.|      |
plant   216 TMLNLGSNSVDGPFPKWICKVKDLYALDLSNNHFNGSIPQCLKYSTYFHTLNLRNNSLSGVLPNL 280

  Fly   335 DIPDSIGNLKSLVRLGMRYNRL-SSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITL 398
            .|.||  .|:|   |.:..|.| ..:|.:|.||:.::..||:||.|.......|.||..|..:.|
plant   281 FIKDS--QLRS---LDVSSNNLVGKLPKSLINCERIEFLNVKGNKIMDTFPFWLGSLPYLKVLML 340

  Fly   399 SRNQFASYPTGGPAQFTNVYSINL----EHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIG 459
            ..|.|.. |...|:.:....||.:    .:|.:..:|...|:        |..|..|.....||.
plant   341 GSNAFYG-PVYNPSAYLGFPSIRIIDISNNNFVGSLPQDYFA--------NWLEMSLVWSGSDIP 396

  Fly   460 TWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNL-RKLRILDLEENRIE-V 522
            .:..|..:|.:|.       |.::|           :.|.:......: .....:|...||.. .
plant   397 QFKYMGNVNFSTY-------DSIDL-----------VYKGVETDFDRIFEGFNAIDFSGNRFSGH 443

  Fly   523 LPHEIGLLHELQRLILQTNQIT-MLPRSIGHLGNLTHLSVSENNLQ-FLPEEIGSLESLENLYIN 585
            :|..||||.||:.|.|..|..| .:|.|:.::.||..|.:|.|||. .:|..:|.|..|.|...:
plant   444 IPGSIGLLSELRLLNLSGNAFTGNIPPSLANITNLESLDLSRNNLSGEIPISLGKLSFLSNTNFS 508

  Fly   586 QN 587
            .|
plant   509 YN 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	5/30 (17%)
		leucine-rich repeat	185..207	CDD:275380	8/22 (36%)
		LRR_RI	204..401	CDD:238064	60/209 (29%)
		LRR_8	207..264	CDD:290566	16/58 (28%)
		leucine-rich repeat	208..230	CDD:275380	5/22 (23%)
		leucine-rich repeat	231..253	CDD:275380	8/22 (36%)
		LRR_8	252..310	CDD:290566	16/60 (27%)
		leucine-rich repeat	254..276	CDD:275380	4/23 (17%)
		leucine-rich repeat	277..299	CDD:275380	7/22 (32%)
		LRR_8	299..356	CDD:290566	19/63 (30%)
		leucine-rich repeat	300..322	CDD:275380	7/22 (32%)
		leucine-rich repeat	323..345	CDD:275380	9/27 (33%)
		LRR_8	344..403	CDD:290566	19/59 (32%)
		leucine-rich repeat	346..368	CDD:275380	7/22 (32%)
		leucine-rich repeat	369..392	CDD:275380	8/22 (36%)
		LRR_RI	<379..566	CDD:238064	47/193 (24%)
		leucine-rich repeat	417..440	CDD:275380	5/26 (19%)
		leucine-rich repeat	441..486	CDD:275380	10/44 (23%)
		LRR_8	463..520	CDD:290566	8/57 (14%)
		leucine-rich repeat	487..507	CDD:275380	1/19 (5%)
		leucine-rich repeat	510..532	CDD:275380	8/22 (36%)
		LRR_8	532..588	CDD:290566	21/58 (36%)
		leucine-rich repeat	556..578	CDD:275380	9/22 (41%)
		leucine-rich repeat	603..626	CDD:275380
RLP36	NP_188941.1	LRR_RI	<16..201	CDD:238064	30/114 (26%)
		leucine-rich repeat	22..44	CDD:275380
		leucine-rich repeat	45..68	CDD:275380
		leucine-rich repeat	69..92	CDD:275380	2/5 (40%)
		leucine-rich repeat	93..117	CDD:275380	1/23 (4%)
		LRR_8	116..176	CDD:290566	18/59 (31%)
		leucine-rich repeat	118..141	CDD:275380	8/22 (36%)
		leucine-rich repeat	142..165	CDD:275380	5/22 (23%)
		leucine-rich repeat	166..189	CDD:275380	8/22 (36%)
		leucine-rich repeat	239..262	CDD:275380	7/22 (32%)
		leucine-rich repeat	263..286	CDD:275380	8/24 (33%)
		LRR_8	264..321	CDD:290566	21/61 (34%)
		leucine-rich repeat	287..310	CDD:275380	9/25 (36%)
		leucine-rich repeat	311..334	CDD:275380	8/22 (36%)
		leucine-rich repeat	361..403	CDD:275380	10/49 (20%)
		leucine-rich repeat	404..477	CDD:275380	21/90 (23%)
		leucine-rich repeat	478..499	CDD:275380	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54393
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010