DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sur-8 and PIRL9

DIOPT Version :9

Sequence 1:	NP_001262665.1	Gene:	Sur-8 / 42093	FlyBaseID:	FBgn0038504	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_187741.2	Gene:	PIRL9 / 820306	AraportID:	AT3G11330	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	270	Identity:	84/270 - (31%)
Similarity:	138/270 - (51%)	Gaps:	3/270 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 ETRPKMVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPSTVKEC 182
            |...::|.:............:....::.:::|:..||......:.|:|||...:.::|......
plant   156 EAEERLVRIYESAEKNAAEDEENVAAVEVNEEVVGILQHASANPVDRVDLSGRKLRLLPEAFGRI 220

  Fly   183 VHLTELYLYSNKIGQLPPEIGCLVSLRNLALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPV 247
            ..|..|.|.:||:..:|..|..|.||..|.::.|||.:||:|:...|:||:|::..|||..:|..
plant   221 QGLLVLNLSNNKLESIPDSIAGLHSLVELDVSTNSLETLPDSIGLLSKLKILNVSTNKLTSLPDS 285

  Fly   248 IYRLRSLTTLYLRFNRITAVADDL-RQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLE 311
            |.|..||..|.:.|||:|.:..:: .:||||..|.::.||||...::||.:.:|..||...|.|.
plant   286 ICRCGSLVILDVSFNRLTYLPTNIGPELVNLEKLLVQYNKIRSFPTSIGEMRSLKHLDAHFNELN 350

  Fly   312 HLPEDIGNCVNLSALDLQHN--ELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNV 374
            .||:......||..|:|..|  :|.|:|.|.|.|.||..|.:..|::.::|.|.....|:.:.||
plant   351 GLPDSFVLLTNLEYLNLSSNFSDLKDLPFSFGELISLQELDLSNNQIHALPDTFGTLDSLTKLNV 415

  Fly   375 EGNGITQLPD 384
            :.|.:...|:
plant   416 DQNPLVVPPE 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sur-8	NP_001262665.1	leucine-rich repeat	163..184	CDD:275380	5/20 (25%)
		leucine-rich repeat	185..207	CDD:275380	8/21 (38%)
		LRR_RI	204..401	CDD:238064	67/184 (36%)
		LRR_8	207..264	CDD:290566	24/56 (43%)
		leucine-rich repeat	208..230	CDD:275380	8/21 (38%)
		leucine-rich repeat	231..253	CDD:275380	9/21 (43%)
		LRR_8	252..310	CDD:290566	22/58 (38%)
		leucine-rich repeat	254..276	CDD:275380	7/22 (32%)
		leucine-rich repeat	277..299	CDD:275380	8/21 (38%)
		LRR_8	299..356	CDD:290566	22/58 (38%)
		leucine-rich repeat	300..322	CDD:275380	7/21 (33%)
		leucine-rich repeat	323..345	CDD:275380	10/23 (43%)
		LRR_8	344..403	CDD:290566	11/41 (27%)
		leucine-rich repeat	346..368	CDD:275380	5/21 (24%)
		leucine-rich repeat	369..392	CDD:275380	4/16 (25%)
		LRR_RI	<379..566	CDD:238064	1/6 (17%)
		leucine-rich repeat	417..440	CDD:275380
		leucine-rich repeat	441..486	CDD:275380
		LRR_8	463..520	CDD:290566
		leucine-rich repeat	487..507	CDD:275380
		leucine-rich repeat	510..532	CDD:275380
		LRR_8	532..588	CDD:290566
		leucine-rich repeat	556..578	CDD:275380
		leucine-rich repeat	603..626	CDD:275380
PIRL9	NP_187741.2	leucine-rich repeat	202..222	CDD:275380	5/19 (26%)
		LRR_RI	205..397	CDD:238064	70/191 (37%)
		LRR_8	222..279	CDD:290566	22/56 (39%)
		leucine-rich repeat	223..245	CDD:275380	8/21 (38%)
		leucine-rich repeat	246..268	CDD:275380	8/21 (38%)
		leucine-rich repeat	269..291	CDD:275380	9/21 (43%)
		leucine-rich repeat	292..315	CDD:275380	7/22 (32%)
		LRR_8	315..370	CDD:290566	20/54 (37%)
		leucine-rich repeat	316..338	CDD:275380	8/21 (38%)
		leucine-rich repeat	339..361	CDD:275380	7/21 (33%)
		LRR_8	360..420	CDD:290566	21/59 (36%)
		leucine-rich repeat	362..386	CDD:275380	10/23 (43%)
		leucine-rich repeat	387..409	CDD:275380	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3538
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910